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[鼻腔上皮-肌上皮癌]

[Epithelial-myoepithelial carcinoma of the nasal cavity].

作者信息

M'sakni I, Laabidi B, Bougrine F, Sabbegh-Znaïdi N, Benzarti S, Chebbi K, Bouziani A

机构信息

Service d'anatomie et de cytologie pathologiques, hôpital militaire de Tunis, Tunisie.

出版信息

Ann Otolaryngol Chir Cervicofac. 2007 Nov;124(5):228-31. doi: 10.1016/j.aorl.2007.04.006. Epub 2007 Sep 4.

Abstract

OBJECTIVES

Epithelial-myoepithelial carcinoma is a rare tumor of the salivary glands with an incidence of less than 1%. Most cases arise in the parotid gland. Extraoral location is exceptional. The purpose of this study was to describe a case with nasal location, which is exceptionally reported in the literature.

MATERIALS AND METHODS

We report a case of epithelial-myoepithelial carcinoma arising in the nasal cavity of a 54-year-old woman.

RESULTS

The woman presented with right recurrent epistaxis and on nasal endoscopic examination was found to have a polypoid tumor in the right nasal cavity. The CT-scan demonstrated a soft tissue mass without extension to the rhinopharynx or bony destruction. Histopathologic examination revealed the tumor to consist of a mixture of a solid, tubular, and trabecular structures with a double-layered arrangement of inner eosinophilic cells and outer clear cells. Dual differentiation toward myoepithelial and epithelial cells was confirmed immunohistochemically.

CONCLUSION

The occurrence of epithelial-myoepithelial carcinoma in the nasal cavity is possible. In published cases, no recurrence or metastasis has been reported in this location.

摘要

目的

上皮-肌上皮癌是一种罕见的涎腺肿瘤,发病率低于1%。大多数病例发生于腮腺。口外部位罕见。本研究的目的是描述1例发生于鼻腔的病例,该病例在文献中鲜有报道。

材料与方法

我们报告1例54岁女性鼻腔发生上皮-肌上皮癌的病例。

结果

该女性表现为右侧反复鼻出血,鼻内镜检查发现右侧鼻腔有一息肉样肿物。CT扫描显示为软组织肿块,未累及鼻咽部或骨质破坏。组织病理学检查显示肿瘤由实性、管状和小梁状结构混合组成,内层为嗜酸性细胞,外层为透明细胞,呈双层排列。免疫组化证实肿瘤具有肌上皮和上皮细胞的双重分化。

结论

鼻腔可发生上皮-肌上皮癌。在已发表的病例中,该部位未见复发或转移的报道。

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