Flam Juliette O, Brook Christopher D, Sobel Rachel, Lee John C, Platt Michael P
Boston University School of Medicine, Boston, Massachusetts, USA.
Allergy Rhinol (Providence). 2015 Jan;6(2):133-7. doi: 10.2500/ar.2015.6.0127.
Epithelial myoepithelial carcinoma (EMC) of the nasal cavity is a rare tumor, and here we describe the first case of EMC of the nasal cavity presenting with epiphora. A case presentation and review of the literature is provided.
A case report is described of a 63-year-old man who presented with unilateral epiphora and was found via a thorough history and physical examination to have a nasal tumor. The physical examination consisted of an ocular examination, including probing and irrigation, and a detailed nasal examination (anterior rhinoscopy, nasal endoscopy). The nasal examination was prompted by the patient's report of concurrent nasal symptoms during history taking. Immunohistochemistry subsequently identified the nasal tumor as EMC. A literature search was performed to gain insights into similar malignancies of the nasal cavity.
Eight cases of EMC of the nasal cavity were identified in the literature, none of the patients presented with epiphora. The case presented here resulted in resolution of the patient's symptoms and no evidence of disease after surgical excision.
Epithelial myoepithelial is a rare salivary gland malignancy that can arise in the nasal cavity. Unilateral epiphora with concurrent nasal symptoms should prompt nasal cavity examination for the possibility of an obstructive tumor.
鼻腔上皮-肌上皮癌（EMC）是一种罕见肿瘤，在此我们描述首例表现为溢泪的鼻腔EMC病例。本文提供了病例报告并对相关文献进行综述。
描述了一名63岁男性病例，该患者出现单侧溢泪，经全面病史询问和体格检查发现鼻腔有肿瘤。体格检查包括眼部检查（包括泪道探通和冲洗）以及详细的鼻腔检查（前鼻镜检查、鼻内镜检查）。鼻腔检查是因患者在病史询问过程中提及同时存在鼻腔症状而进行的。免疫组化随后将鼻腔肿瘤确诊为EMC。进行文献检索以深入了解鼻腔类似恶性肿瘤情况。
文献中确定了8例鼻腔EMC病例，无一例患者表现为溢泪。本文所述病例经手术切除后患者症状缓解且无疾病证据。
上皮-肌上皮癌是一种罕见的涎腺恶性肿瘤，可发生于鼻腔。单侧溢泪并伴有鼻腔症状应促使对鼻腔进行检查，以排除阻塞性肿瘤的可能性。
