Chernevskaia O M, Brusnigina N F
Antibiot Khimioter. 1991 Sep;36(9):7-9.
Resistance of 159 strains of opportunistic enterobacteria to 9 antibacterial drugs was studied. The strains were isolated from man and cattle. It was shown that the overwhelming majority of the isolates (93 per cent) were polyresistant irrespective of the genus. There was a high frequency of the strains resistant to the widely used antibiotics such as chloramphenicol (73 per cent), ampicillin (73.6 per cent) and rifampicin (95.6 per cent) and sulfanilamides (99.3 per cent). Gentamicin and nalidixic acid proved to be the most active against the cultures: 11.9 and 10 per cent of the resistant strains, respectively. The strains of enterobacteria isolated from different sources had a sensitivity to the antibiotics. Multiple antibiotic resistance to at least 5 drugs, variability of the spectra and high resistance were more characteristic of the isolates from the animals. The necessity of a rational use of antibacterial drugs in veterinary is indicated.
对159株机会性肠道杆菌对9种抗菌药物的耐药性进行了研究。这些菌株分离自人和牛。结果表明,绝大多数分离株(93%)无论属于何种菌属均具有多重耐药性。对广泛使用的抗生素如氯霉素(73%)、氨苄西林(73.6%)、利福平(95.6%)和磺胺类药物(99.3%)耐药的菌株出现频率很高。庆大霉素和萘啶酸对这些培养物最为有效:耐药菌株分别为11.9%和10%。从不同来源分离的肠道杆菌菌株对抗生素有敏感性。对至少5种药物的多重耐药性、谱的变异性和高耐药性在动物分离株中更为常见。这表明在兽医领域合理使用抗菌药物的必要性。