Pang Daniel S, Boysen Søren
Department of Anaesthesia, Faculty of Veterinary Medicine, Companion Animal Clinic, University of Montreal, Saint-Hyacinthe, Quebec, Canada.
J Am Anim Hosp Assoc. 2007 Sep-Oct;43(5):270-9. doi: 10.5326/0430270.
The measurement of blood lactate in people has proven to be a useful tool in the diagnosis, monitoring, and prognosis of a wide range of clinical syndromes. Its use in small animals is increasing, and several studies have been completed that demonstrate its potential role in critical care. This article summarizes the current state of knowledge regarding the physiology and pathophysiology of lactate production and lactic acidosis; current indications and the utility of measurement in a critical care setting are described; novel applications in the evaluation of cavitary effusions are highlighted; and a guide to the therapy of lactic acidosis is presented.
在人类中，血液乳酸测量已被证明是诊断、监测和预测多种临床综合征的有用工具。其在小动物中的应用正在增加，并且已经完成了几项研究，证明了其在重症监护中的潜在作用。本文总结了关于乳酸生成和乳酸性酸中毒的生理学和病理生理学的当前知识状态；描述了当前的适应症以及在重症监护环境中测量的效用；强调了在评估空洞性积液中的新应用；并提供了乳酸性酸中毒的治疗指南。
