Núcleo de Nutrição, Laboratório de Bioquímica da Nutrição, Faculdade de Ciências da Saúde, Universidade de Brasília, Campus Universitário Darcy Ribeiro-Asa Norte. CEP 70910-900 Brasília-DF, Brazil.
Int J Environ Res Public Health. 2011 Aug;8(8):3216-31. doi: 10.3390/ijerph8083216. Epub 2011 Aug 3.
Coffee has been associated with reductions in the risk of non-communicable chronic diseases (NCCD), including diabetes mellitus. Because differences in food habits are recognizable modifying factors in the epidemiology of diabetes, we studied the association of coffee consumption with type-2 diabetes in a sample of the adult population of the Federal District, Brazil. This cross-sectional study was conducted by telephone interview (n = 1,440). A multivariate analysis was run controlling for socio-behavioural variables, obesity and family antecedents of NCCD. A hierarchical linear regression model and a Poisson regression were used to verify association of type-2 diabetes and coffee intake. The independent variables which remained in the final model, following the hierarchical inclusion levels, were: first level-age and marital status; second level-diabetes and dyslipidaemias in antecedents; third level-cigarette smoking, supplement intake, body mass index; and fourth level-coffee intake (≤100 mL/d, 101 to 400 mL/day, and >400 mL/day). After adjusting hierarchically for the confounding variables, consumers of 100 to 400 mL of coffee/day had a 2.7% higher (p = 0.04) prevalence of not having diabetes than those who drank less than 100 mL of coffee/day. Compared to coffee intake of ≤100 mL/day, adults consuming >400 mL of coffee/day showed no statistically significant difference in the prevalence of diabetes. Thus, moderate coffee intake is favourably associated with self-reported type-2 diabetes in the studied population. This is the first study to show a relationship between coffee drinking and diabetes in a Brazilian population.
咖啡与非传染性慢性病(NCCD)风险降低有关,包括糖尿病。由于饮食习惯的差异是糖尿病发生的可识别的调节因素,我们在巴西联邦区的成年人群体中研究了咖啡消费与 2 型糖尿病之间的关系。这项横断面研究通过电话访谈进行(n=1440)。在控制社会行为变量、肥胖和 NCCD 家族史的情况下进行多变量分析。使用分层线性回归模型和泊松回归来验证 2 型糖尿病与咖啡摄入量之间的关联。在分层纳入水平之后,最终模型中保留的自变量为:一级-年龄和婚姻状况;二级-糖尿病和先证疾病的血脂异常;三级-吸烟、补充剂摄入、体重指数;以及四级-咖啡摄入量(≤100 mL/d、101 至 400 mL/天和>400 mL/天)。在对混杂变量进行分层调整后,每天饮用 100 至 400 毫升咖啡的消费者患糖尿病的比例比每天饮用少于 100 毫升咖啡的消费者高 2.7%(p=0.04)。与每天饮用≤100 毫升咖啡相比,每天饮用>400 毫升咖啡的成年人患糖尿病的比例没有统计学上的显著差异。因此,适度饮用咖啡与研究人群中自我报告的 2 型糖尿病呈有利关联。这是第一项表明巴西人群中咖啡饮用与糖尿病之间存在关系的研究。