Panagiotakos Demosthenes, Bountziouka Vassiliki, Zeimbekis Akis, Vlachou Ioanna, Polychronopoulos Evangelos
Department of Nutrition Science and Dietetics, Harokopio University, Athens, Greece.
J Med Food. 2007 Dec;10(4):615-21. doi: 10.1089/jmf.2007.414.
The effect of various foods on the development of cardiovascular disease (CVD) has already been investigated. We performed a food pattern analysis and evaluated the association between the consumption of various patterns and the prevalence of CVD risk factors among elderly people from Mediterranean islands (the MEDIS study). During 2005-2006, 300 men and women from Cyprus, 142 from Mitilini, 100 from Samothraki, and 104 from Kefalonia islands (65-100 years old) were enrolled. CVD risk factors (i.e., hypertension, diabetes, hypercholesterolemia, and obesity) were assessed through standard procedures. All participants were asked about their usual frequency of consumption of various foods through a semiquantitative food frequency questionnaire, and food pattern analysis using the principal components analysis (PCA) method was then performed. PCA extracted five components that explained the 56.53% of the total variation in intake: i.e., a food pattern (component 1) that was loaded mainly on low-fat products, a high glycemic index and high-fat pattern (component 2), a pattern that included consumption of cereals and sweets (component 3), a pattern that was characterized by the intake of dairy products and fruits (component 4), and a pattern that was characterized by the consumption of alcoholic beverages (component 5). Ordinal logistic regression analysis revealed that component 1, component 3, and component 5 were associated with lower likelihood of having increased burden of CVD (P < .01), irrespective of various potential confounders. Food pattern analysis revealed the current nutritional status of our elderly participants, and provided a pathway for reducing the burden of CVD risk factors among these people.
各种食物对心血管疾病(CVD)发展的影响已得到研究。我们进行了食物模式分析,并评估了不同模式的食物消费与地中海岛屿老年人CVD危险因素患病率之间的关联(MEDIS研究)。在2005年至2006年期间,招募了来自塞浦路斯的300名男性和女性、来自米蒂利尼的142人、来自萨莫色雷斯的100人以及来自凯法利尼亚岛的104人(年龄在65至100岁之间)。通过标准程序评估CVD危险因素(即高血压、糖尿病、高胆固醇血症和肥胖)。通过半定量食物频率问卷询问所有参与者各种食物的通常消费频率,然后使用主成分分析(PCA)方法进行食物模式分析。PCA提取了五个成分,它们解释了摄入量总变异的56.53%:即主要以低脂产品为主的食物模式(成分1)、高血糖指数和高脂肪模式(成分2)、包括谷物和甜食消费的模式(成分3)、以乳制品和水果摄入为特征的模式(成分4)以及以酒精饮料消费为特征的模式(成分5)。有序逻辑回归分析显示,无论各种潜在混杂因素如何,成分1、成分3和成分5与CVD负担增加的可能性较低相关(P <.01)。食物模式分析揭示了我们老年参与者的当前营养状况,并为减轻这些人群中CVD危险因素的负担提供了一条途径。