Pedrinazzi Claudio, Durin Ornella, Agricola Pietro, Romagnoli Piergiulio, Inama Giuseppe
Department of Cardiology, Ospedale Maggiore, l.go U. Dossena, 2, 26013, Crema, Italy.
J Interv Card Electrophysiol. 2007 Sep;19(3):179-85. doi: 10.1007/s10840-007-9153-6. Epub 2007 Sep 5.
Radiofrequency (RF) catheter ablation has not been widely undertaken in elderly patients. The aim of our study was to compare the success rate of radiofrequency ablation and the incidence of severe procedural complications in young-adult and elderly patients.
We enrolled all patients undergoing radiofrequency catheter ablation procedures for supraventricular and ventricular arrhythmias at our Cardiology Department from January 2000 to December 2005. The patients were divided into two groups according to age: patients aged <70 years (group A) and those aged >or=70 years (group B). Group B was then divided into two subgroups: B1 (age 70-79 years) and B2 (age >or=80 years). We recorded the incidence of procedural complications and the long-term efficacy (mean follow-up 46 +/- 20 months).
We studied 605 patients, 69% in group A and 31% in group B (24% in subgroup B1 and 7% in B2). The prevalence of structural heart disease was higher in elderly patients than in young adults (83 vs 37%, p < 0.01). The rate of procedural complications was 1.3%; no differences emerged between groups A and B (1.2 vs 1.5%, p = NS) or among groups A, B1 and B2 (1.2 vs 1.4 vs 2%, p = NS). The success rate of catheter ablation was 91%, with no differences between the age-groups (92 vs 88%, p = NS) or among groups A, B1 and B2 (92 vs 88 vs 88%, p = NS).
Catheter ablation in elderly and very elderly patients is as effective and safe as in young-adult subjects, at least in cases which do not require left heart catheterization.
射频(RF)导管消融术在老年患者中尚未广泛开展。我们研究的目的是比较青年和老年患者射频消融的成功率及严重手术并发症的发生率。
我们纳入了2000年1月至2005年12月在我院心内科接受室上性和室性心律失常射频导管消融术的所有患者。根据年龄将患者分为两组:年龄<70岁的患者(A组)和年龄≥70岁的患者(B组)。然后将B组分为两个亚组:B1(年龄70 - 79岁)和B2(年龄≥80岁)。我们记录了手术并发症的发生率和长期疗效(平均随访46±20个月)。
我们研究了605例患者,A组占69%,B组占31%(B1亚组占24%,B2亚组占7%)。老年患者结构性心脏病的患病率高于青年患者(83%对37%,p<0.01)。手术并发症发生率为1.3%;A组和B组之间(1.2%对1.5%,p = 无显著性差异)或A组、B1组和B2组之间(1.2%对1.4%对2%,p = 无显著性差异)均无差异。导管消融的成功率为91%,各年龄组之间(92%对88%,p = 无显著性差异)或A组、B1组和B2组之间(92%对88%对88%,p = 无显著性差异)均无差异。
至少在不需要左心导管检查的情况下,老年和高龄患者的导管消融与青年患者一样有效和安全。