Sripipatana Tabitha, Spensley Allison, Miller Anna, McIntyre James, Sangiwa Gloria, Sawe Frederick, Jones David, Wilfert Catherine M
Elizabeth Glaser Pediatric AIDS Foundation, Washington, DC, USA.
Am J Obstet Gynecol. 2007 Sep;197(3 Suppl):S107-12. doi: 10.1016/j.ajog.2007.03.069.
This article reviews the experiences of programs designed to provide access to prevention of mother-to-child transmission services with the goal of improving services in resource-constrained settings. The article reports new data from the Elizabeth Glaser Pediatric AIDS Foundation's prevention of mother-to-child transmission program in sub-Saharan Africa, which has provided human immunodeficiency virus testing to more than 1,300,000 pregnant women and antiretroviral prophylaxis to 134,000 human immunodeficiency virus-infected pregnant women and more than 78,000 human immunodeficiency virus-exposed infants. Review of qualitative program data highlights the practical innovations that sites are implementing to improve the uptake of prevention of mother-to-child transmission services. Recommendations discussed include opt-out counseling and testing, rapid human immunodeficiency virus testing in antenatal care, counseling and testing in maternity, and provision of antiretroviral prophylaxis for mother and infant at the time of human immunodeficiency virus testing. Successful programmatic innovations need to be disseminated widely as more aggressive prevention strategies must be implemented to increase access to more than 10% of pregnant women worldwide.
本文回顾了旨在提供预防母婴传播服务的项目经验，目标是改善资源有限环境下的服务。文章报告了伊丽莎白·格拉泽儿童艾滋病基金会在撒哈拉以南非洲的预防母婴传播项目的新数据，该项目已为超过130万名孕妇提供了人类免疫缺陷病毒检测，为13.4万名感染人类免疫缺陷病毒的孕妇和超过7.8万名接触过人类免疫缺陷病毒的婴儿提供了抗逆转录病毒药物预防。对项目定性数据的回顾突出了各项目点为提高预防母婴传播服务的接受率而实施的实际创新措施。讨论的建议包括主动咨询和检测、产前护理中的快速人类免疫缺陷病毒检测、产科咨询和检测，以及在进行人类免疫缺陷病毒检测时为母婴提供抗逆转录病毒药物预防。成功的项目创新需要广泛传播，因为必须实施更积极的预防策略，以确保全球超过10%的孕妇能够获得相关服务。
