von Koskull-Döring Pascal, Scharf Klaus-Dieter, Nover Lutz
Department of Molecular Cell Biology, J. W. Goethe University, Biocenter, Max-von-Laue-Str. 9, D-60438 Frankfurt am Main, Germany.
Trends Plant Sci. 2007 Oct;12(10):452-7. doi: 10.1016/j.tplants.2007.08.014. Epub 2007 Sep 7.
Compared with other eukaryotes with one to three heat stress transcription factors (Hsf), the plant Hsf family shows a striking multiplicity, with more than 20 members. Despite many conserved features, members of the Hsf family show a strong diversification of expression pattern and function within the family. Research on Arabidopsis Hsfs opened a new era with genome-wide transcriptome profiling in combination with the availability of knockout lines. The output from these analyses provides increasing evidence that individual Hsfs have unique functions as part of different signal transduction pathways operating in response to environmental stress and during development.
与具有一至三个热应激转录因子（Hsf）的其他真核生物相比，植物Hsf家族呈现出显著的多样性，有20多个成员。尽管有许多保守特征，但Hsf家族成员在家族内部表现出表达模式和功能的强烈分化。对拟南芥Hsf的研究结合基因敲除系的可得性，开启了全基因组转录组分析的新时代。这些分析的结果提供了越来越多的证据，表明单个Hsf作为响应环境胁迫和发育过程中不同信号转导途径的一部分，具有独特的功能。
