糖尿病与高血糖症中的感染

Infections in diabetes mellitus and hyperglycemia.

作者信息

Gupta Smita, Koirala Janak, Khardori Romesh, Khardori Nancy

机构信息

Division of Endocrinology, Metabolism and Molecular Medicine, Southern Illinois University School of Medicine, 701 North First Street, D-405B, PO Box 19636, Springfield, IL 62794-9636, USA.

出版信息

Infect Dis Clin North Am. 2007 Sep;21(3):617-38, vii. doi: 10.1016/j.idc.2007.07.003.

DOI:10.1016/j.idc.2007.07.003

PMID:17826615

Abstract

Infections in diabetes mellitus are relatively more common and serious. Diabetic patients run the risk of acute metabolic decompensation during infections, and conversely patients with metabolic decompensation are at higher risk of certain invasive infections. Tight glycemic control is of paramount importance during acute infected or high stress state. Infections in diabetic patients result in extended hospital stays and additional financial burden. Given the risks of not alleviating the metabolic dysregulation and the benefits of decent glycemic control, it is necessary that besides antimicrobial therapy, equal emphasis be placed on intensified glycemic control.

摘要

糖尿病患者的感染相对更为常见且严重。糖尿病患者在感染期间有发生急性代谢失代偿的风险，反之，代谢失代偿的患者发生某些侵袭性感染的风险更高。在急性感染或高应激状态下，严格控制血糖至关重要。糖尿病患者的感染会导致住院时间延长和额外的经济负担。鉴于不缓解代谢失调的风险以及良好血糖控制的益处，除抗菌治疗外，同样重视强化血糖控制是必要的。