Diba Kamran, Buzsáki György
Center for Molecular and Behavioral Neurobiology, Rutgers University, 197 University Ave, Newark, New Jersey 07102, USA.
Nat Neurosci. 2007 Oct;10(10):1241-2. doi: 10.1038/nn1961. Epub 2007 Sep 2.
We report that temporal spike sequences from hippocampal place neurons of rats on an elevated track recurred in reverse order at the end of a run, but in forward order in anticipation of the run, coinciding with sharp waves. Vector distances between the place fields were reflected in the temporal structure of these sequences. This bidirectional re-enactment of temporal sequences may contribute to the establishment of higher-order associations in episodic memory.
我们报告称,在高架轨道上的大鼠海马位置神经元的时间尖峰序列在奔跑结束时以相反顺序重现,但在预期奔跑时以正向顺序重现,这与尖波同时出现。位置场之间的向量距离反映在这些序列的时间结构中。这种时间序列的双向重演可能有助于情景记忆中高阶关联的建立。