1978年至1988年间北欧国家镇痛药和抗炎药的消费情况。

Consumption of analgesics and anti-inflammatory drugs in the nordic countries between 1978-1988.

作者信息

Ahonen R, Enlund H, Klaukka T, Martikainen J

机构信息

University of Kuopio, Department of Social Pharmacy, Finland.

出版信息

Eur J Clin Pharmacol. 1991;41(1):37-42. doi: 10.1007/BF00280103.

DOI:10.1007/BF00280103

PMID:1782974

Abstract

Comparative wholesale statistics from the five Nordic countries show an increase of 15-42% in the total consumption of analgesics and anti-inflammatory drugs (including antirheumatics) in the period 1978-1988. Denmark had the highest total consumption (112 DDD/1000 inhab/day in 1988) and Norway had the lowest (61 DDD/1000 inhab/day). Iceland and Finland, with the highest increases in total consumption (45% and 35%), overtook Norway in the early to mid 1980's. Division of total consumption into subgroups showed that Denmark had the highest consumption of analgesics (90 DDDs) and that Finland and Iceland had the lowest figure. The latter countries, however, had the highest consumption of nonsteroidal anti-inflammatory drugs (NSAID), 35 and 30 DDDs, respectively, in 1988. The increase in NSAID consumption was 57% in Finland and 54% in Iceland, while Denmark had only an 18% increase. The new NSAIDs introduced in the 1970's appear to have increased the overall consumption of pain relievers in the Nordic countries, especially in Finland and Iceland.

摘要

来自北欧五国的比较性批发统计数据显示，1978年至1988年期间，镇痛药和抗炎药（包括抗风湿药）的总消费量增长了15%至42%。丹麦的总消费量最高（1988年为112限定日剂量/1000居民/天），挪威最低（61限定日剂量/1000居民/天）。冰岛和芬兰的总消费量增长幅度最大（分别为45%和35%），在20世纪80年代初至中期超过了挪威。将总消费量细分为不同亚组后发现，丹麦的镇痛药消费量最高（90限定日剂量），而芬兰和冰岛的消费量最低。然而，后两个国家的非甾体抗炎药消费量最高，1988年分别为35和30限定日剂量。芬兰的非甾体抗炎药消费量增长了57%，冰岛增长了54%，而丹麦仅增长了18%。20世纪70年代推出的新型非甾体抗炎药似乎增加了北欧国家止痛药的总体消费量，尤其是在芬兰和冰岛。