Cottone M, Cipolla C, Orlando A, Oliva L, Aiala R, Puleo A
Istituto di Medicina Generale e Pneumologia, Clinica Medica R, Università di Palermo, Italy.
Eur J Epidemiol. 1991 Nov;7(6):636-40. doi: 10.1007/BF00218674.
An epidemiologic study of Crohn's disease was carried out in the Province of Palermo, Italy, between 1987 and 1989. The incidence of first hospitalization was prospectively evaluated in this period. A total of 103 patients (59 males, 44 females) were diagnosed. The standardized annual incidence was 2.7/100,000. The incidence was quite constant during the 3 years of the study (1987: 2.9/100,000; 1988: 2.4/100,000; 1989: 2.99/100,000). Incidence rates were slightly higher in men than in women. The disease had a bimodal age distribution in female (with peaks at age 20-29 and 60-69) and males (with peaks at age 30-39, 40-49). No cases were observed at age 0-9. The incidence of Crohn's disease in southern Italy is comparable to that reported in northern Europe.
1987年至1989年间，在意大利巴勒莫省开展了一项克罗恩病的流行病学研究。在此期间，对首次住院发病率进行了前瞻性评估。共诊断出103例患者（59例男性，44例女性）。标准化年发病率为2.7/10万。在研究的3年期间（1987年：2.9/10万；1988年：2.4/10万；1989年：2.99/10万）发病率相当稳定。男性发病率略高于女性。该病在女性（20 - 29岁和60 - 69岁出现峰值）和男性（30 - 39岁、40 - 49岁出现峰值）中呈双峰年龄分布。0 - 9岁未观察到病例。意大利南部克罗恩病的发病率与北欧报道的发病率相当。
