Garland C F, Lilienfeld A M, Mendeloff A I, Markowitz J A, Terrell K B, Garland F C
Gastroenterology. 1981 Dec;81(6):1115-24.
A study was carried out during 1973 to determine the incidence of first hospitalizations for ulcerative colitis and Crohn's disease in 15 areas of the United States, including communities of widely varied size, climatic, ethnic, racial, and socioeconomic characteristics. The following descriptions apply to incidence rates per 100,000 population for the aggregate of the 15 areas. Ulcerative colitis had a bimodal age distribution in white males (with peaks at ages 20-29 and 70-79 yr) and females (with peaks at ages 30-39 and 70-79 yr). Crohn's disease had a bi- or trimodal age distribution in white males (with peaks at ages 20-29, 50-59, and 70-79 yr) and females (with peaks at ages 20-29, 50-59, and 70-79 yr). The age, sex, and geographic distributions that were observed in this study may have important etiologic implications.
1973年开展了一项研究，以确定美国15个地区溃疡性结肠炎和克罗恩病首次住院的发病率，这些地区包括规模、气候、种族、民族和社会经济特征差异很大的社区。以下描述适用于这15个地区总人口中每10万人的发病率。溃疡性结肠炎在白人男性（发病高峰在20 - 29岁和70 - 79岁）和女性（发病高峰在30 - 39岁和70 - 79岁）中呈现双峰年龄分布。克罗恩病在白人男性（发病高峰在20 - 29岁、50 - 59岁和70 - 79岁）和女性（发病高峰在20 - 29岁、50 - 59岁和70 - 79岁）中呈现双峰或三峰年龄分布。本研究中观察到的年龄、性别和地理分布可能具有重要的病因学意义。
