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No evidence of HIV-2 infection in subjects at risk for AIDS living in north-east Italy.

作者信息

Del Mistro A, De Rossi A, Francavilla E, Sartori M T, Chieco-Bianchi L

机构信息

Istituto di Oncologia, Padova, Italy.

出版信息

Eur J Epidemiol. 1991 Nov;7(6):682-5. doi: 10.1007/BF00218682.

DOI:10.1007/BF00218682
PMID:1783062
Abstract

Sera samples from 1134 individuals (824 HIV-1 seropositive and 310 HIV-1 seronegative), collected from January 1988 to April 1990, were tested for HIV-2 antibodies by whole virus assays and synthetic peptide-based assays to determine the prevalence of HIV-2 infection in populations at risk for AIDS in North-East Italy (Veneto Region). Partial reactivities on HIV-2 Western Blot were a common finding in HIV-1 seropositive samples. None of the sera fulfilled the criteria for HIV-2 seropositivity, since only low-level reactivity was observed with an HIV-2 competitive ELISA test, and no reactivity occurred with an HIV-2 specific peptide. Therefore, there is no evidence of HIV-2 infection in this geographical area, to date.

摘要

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本文引用的文献

1
Dual HIV-1 and HIV-2 infection in West Africa supported by synthetic peptide analysis.
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2
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Lancet. 1988 Dec 17;2(8625):1389-91. doi: 10.1016/s0140-6736(88)90586-7.
6
Envelope cross-reactivity in Western blot for HIV-1 and HIV-2 may not indicate dual infection.在针对HIV-1和HIV-2的蛋白质印迹法中,包膜交叉反应性可能并不表明双重感染。
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7
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Lancet. 1988 Jul 16;2(8603):162-3. doi: 10.1016/s0140-6736(88)90712-x.
8
Synthetic peptide immunoassay distinguishes HIV type 1 and HIV type 2 infections.合成肽免疫测定法可区分1型和2型HIV感染。
Science. 1987 Sep 11;237(4820):1346-9. doi: 10.1126/science.2888192.
9
HIV-2 in Brazil.巴西的HIV-2。
Lancet. 1987 Aug 15;2(8555):402. doi: 10.1016/s0140-6736(87)92427-5.
10
HIV-1 and HIV-2 infections in Italian AIDS/ARC patients.意大利艾滋病/艾滋病相关综合征患者中的HIV-1和HIV-2感染
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