Simultaneous isolation of HIV-1 and HIV-2 from an AIDS patient.
作者信息
Evans L A, Moreau J, Odehouri K, Seto D, Thomson-Honnebier G, Legg H, Barboza A, Cheng-Mayer C, Levy J A
机构信息
Department of Medicine, University of California School of Medicine, San Francisco 94143.
出版信息
Lancet. 1988 Dec 17;2(8625):1389-91. doi: 10.1016/s0140-6736(88)90586-7.
PMID:2904524
Abstract
Two distinct human immunodeficiency viruses, HIV-1SF480 and HIV-2UC2 were isolated simultaneously from the blood of an Ivory Coast patient with AIDS. The HIV subtypes were segregated by their differential ability to infect established human cell lines and by the cell surface expression of type-specific viral antigens. The viruses could be distinguished by both immunoblot and Southern blot analyses. The results indicate that an individual can be infected by both HIV subtypes.
摘要
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