Toppano B, Zardini E, Giordano A, Moscolo G
Clinica Ostetrica e Ginecologica, Università degli Studi di Verona.
Minerva Ginecol. 1991 Nov;43(11):537-9.
The Authors report their experience of two pregnancies complicated by polyhydramnios, treated with indomethacin (100 mg/day for 10 and 7 days respectively). The outcome of both pregnancies was foetal intrauterine death. The absence of foetal anomalies incompatible with life and the presence of tissue lesions by asphyxia led the Authors to think that indomethacin might have had a determinant role in the foetal death. This study suggests that the use of indomethacin in polyhydramnios is questionable.
作者报告了他们对两例并发羊水过多的妊娠病例的治疗经验，分别使用吲哚美辛治疗（每天100毫克，分别用药10天和7天）。两例妊娠的结局均为胎儿宫内死亡。由于未发现与生命不相容的胎儿异常，且存在窒息导致的组织损伤，作者认为吲哚美辛可能在胎儿死亡中起了决定性作用。本研究表明，在羊水过多的情况下使用吲哚美辛是值得怀疑的。
