Pfeiffer Christopher D, Kazmierczak James J, Davis Jeffrey P
Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WIS, USA.
WMJ. 2007 Jul;106(4):191-5.
To characterize epidemiologic, clinical, and laboratory features of babesiosis occurring in Wisconsin residents.
Conduct a review of all cases of babesiosis reported to the Wisconsin Division of Public Health with onsets during 1996-2005. For case patients with onsets during 2004, pertinent medical records were reviewed and patient interviews were performed.
Increase awareness of the occurrence and recent trends and facilitate prompt, appropriate diagnosis and treatment of babesiosis. Increase awareness among clinicians of the Infectious Diseases Society of America guidelines for the management of babesiosis, Lyme disease, and human granulocytic anaplasmosis.
The study represents an analysis of data received through passive surveillance of a disease that is officially reportable to the Wisconsin Division of Public Health. Other than the description of the occurrence of babesiosis among Wisconsin residents, there were no planned outcome measures.
Of the 32 cases of babesiosis reported to the DPH during the study interval, 23 (72%) occurred during 2004 and 2005. The majority of cases occurred in northwestern and west-central Wisconsin. At least 6 patients were co-infected with other tick-borne pathogens. Anemia, thrombocytopenia, and elevation of liver transaminase levels were the most notable laboratory abnormalities among case patients.
The apparent increased incidence in babesiosis among Wisconsin residents should impact clinicians' workups for acute febrile illness with known tick exposure, especially in northwest and west central Wisconsin. Babesiosis should now also be considered in patients diagnosed with Lyme disease who have marked constitutional symptoms, especially those with anemia or thrombocytopenia.
描述威斯康星州居民发生的巴贝斯虫病的流行病学、临床和实验室特征。
对1996 - 2005年期间向威斯康星州公共卫生部门报告的所有巴贝斯虫病病例进行回顾。对于2004年发病的病例患者，查阅相关医疗记录并进行患者访谈。
提高对该病发生情况和近期趋势的认识，并促进巴贝斯虫病的及时、恰当诊断和治疗。提高临床医生对美国传染病学会关于巴贝斯虫病、莱姆病和人粒细胞无形体病管理指南的认识。
本研究是对通过被动监测获得的、需向威斯康星州公共卫生部门正式报告的一种疾病的数据进行分析。除了描述威斯康星州居民中巴贝斯虫病的发生情况外，没有计划的观察指标。
在研究期间向公共卫生部门报告的32例巴贝斯虫病病例中，23例（72%）发生在2004年和2005年。大多数病例发生在威斯康星州的西北部和中西部。至少6名患者同时感染了其他蜱传病原体。贫血、血小板减少和肝转氨酶水平升高是病例患者中最显著的实验室异常。
威斯康星州居民中巴贝斯虫病发病率的明显上升应影响临床医生对已知有蜱虫暴露的急性发热疾病的检查，特别是在威斯康星州的西北部和中西部。对于诊断为莱姆病且有明显全身症状的患者，尤其是那些有贫血或血小板减少的患者，现在也应考虑巴贝斯虫病。
