Saitoglu Mahmut, Ardicoglu Ozge, Ozgocmen Salih, Kamanli Ayhan, Kaya Arzu
Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Firat University Faculty of Medicine, Elazig, Turkey.
Arch Med Res. 2007 Oct;38(7):746-51. doi: 10.1016/j.arcmed.2007.03.009. Epub 2007 Jun 7.
Osteoporosis is a systemic and metabolic skeletal disease characterized by reduced bone mass, changes in microarchitecture, and consequential increased fracture risk. Previous reports described a relationship between bone content with fat mass and lean body mass. In this study, we assessed osteoporosis risk factors and the association with somatotypes in males aged 45-65 years.
Standard axial spine and proximal femur bone mineral density (BMD) were measured using dual x-ray (DXA) absorptiometry in 70 healthy men. Heath-Carter procedure was followed to assess individual's somatotype.
All body types were grouped as endomorphy, mesomorphy, and ectomorphy. Moderate to weak correlations were found between lumbar BMD with endomorphy and mesomorphy. Negative correlation was found between lumbar BMD and ectomorphy. Total femur BMD correlated positively with endomorphy and mesomorphy and negatively correlated with ectomorphy. Body mass index correlated weakly with lumbar, femur neck, and total femur BMD. Multiple regression analysis revealed that endomorphy was significantly related to BMD measurements at lumbar spine (standardized coefficient, SC = 0.51, p = 0.001), femur neck (SC = 0.52, p = 0.001), and total femur BMD (SC = 0.41, p = 0.01). Lumbar BMD and age, hand grip strength, smoking, tea and coffee consumption, calorie expenditure, calcium intake, PTH, albumin, total protein, sex hormone-binding globulin, and testosterone were not significantly correlated.
Endomorphy seems related to high BMD values at the lumbar spine and the proximal femur in middle-aged men. Somatotype together with daily calorie expenditure may be taken into account when assessing risk factors for male osteoporosis.
骨质疏松症是一种全身性代谢性骨骼疾病，其特征为骨量减少、微结构改变以及随之而来的骨折风险增加。既往报告描述了骨含量与脂肪量和瘦体重之间的关系。在本研究中，我们评估了45至65岁男性的骨质疏松症风险因素及其与体型的关联。
使用双能X线（DXA）吸收法测量了70名健康男性的标准脊柱和近端股骨骨密度（BMD）。采用希思 - 卡特法评估个体的体型。
所有体型分为内胚层型、中胚层型和外胚层型。腰椎骨密度与内胚层型和中胚层型之间存在中度至弱相关性。腰椎骨密度与外胚层型之间存在负相关性。股骨总骨密度与内胚层型和中胚层型呈正相关，与外胚层型呈负相关。体重指数与腰椎、股骨颈和股骨总骨密度呈弱相关性。多元回归分析显示，内胚层型与腰椎（标准化系数，SC = 0.51，p = 0.001）、股骨颈（SC = 0.52，p = 0.00）和股骨总骨密度（SC = 0.41，p = 0.01）测量值显著相关。腰椎骨密度与年龄、握力、吸烟、茶和咖啡摄入量、卡路里消耗、钙摄入量、甲状旁腺激素、白蛋白、总蛋白、性激素结合球蛋白和睾酮无显著相关性。
内胚层型似乎与中年男性腰椎和近端股骨的高骨密度值相关。在评估男性骨质疏松症风险因素时，可考虑体型以及每日卡路里消耗。
