Zhang Zhao-Fei, Yang Jun-Long, Jiang Huan-Chang, Lai Zheng, Wu Feng, Liu Zhi-Xiang
Department of Orthopedic Surgery, Huadu District People's Hospital of Guangzhou, Guangdong, China.
Medicine (Baltimore). 2017 Mar;96(12):e6437. doi: 10.1097/MD.0000000000006437.
Current studies evaluating the association of tea consumption and bone mineral density (BMD) have yielded inconsistent findings. Therefore, we conducted a meta-analysis to assess the relationship between tea consumption and BMD.
The PubMed, Embase, and Cochrane Library databases were comprehensively searched, and a meta-analysis performed of all observational studies assessing the association of tea consumption and BMD. Forest plots were used to illustrate the results graphically. The Q-test and I statistic were employed to evaluate between-study heterogeneity. Potential publication bias was assessed by the funnel plot.
Four cohort, 1 case-control, and 8 cross-sectional studies including a total of 12,635 cases were included. Tea consumption was shown to prevent bone loss [odds ratio (OR): 0.66; 95% confidence interval (CI), 0.47-0.94; P = 0.02], yielding higher mineral densities in several bones, including the lumbar spine [standardized mean difference (SMD): 0.19; 95% CI, 0.08-0.31; P = 0.001], hip (SMD: 0.19; 95% CI, 0.05-0.34; P = 0.01), femoral neck [mean difference (MD): 0.01; 95% CI, 0.00-0.02; P = 0.04], Ward triangle (MD: 0.02; 95% CI, 0.01-0.04; P = 0.001), and greater trochanter (MD: 0.03; 95% CI, 0.02-0.04; P < 0.00001), than the non-tea consumption group.
This meta-analysis provided a potential trend that tea consumption might be beneficial for BMD, especially in the lumbar spine, hip, femoral neck, Ward triangle, and greater trochanter, which might help prevent bone loss.
目前评估饮茶与骨密度(BMD)之间关联的研究结果并不一致。因此,我们进行了一项荟萃分析,以评估饮茶与骨密度之间的关系。
全面检索了PubMed、Embase和Cochrane图书馆数据库,并对所有评估饮茶与骨密度关联的观察性研究进行了荟萃分析。森林图用于以图形方式说明结果。采用Q检验和I统计量评估研究间的异质性。通过漏斗图评估潜在的发表偏倚。
纳入了四项队列研究、一项病例对照研究和八项横断面研究,共12,635例。结果显示,饮茶可预防骨质流失[比值比(OR):0.66;95%置信区间(CI),0.47 - 0.94;P = 0.02],在包括腰椎[标准化均值差(SMD):0.19;95% CI,0.08 - 0.31;P = 0.001]、髋部(SMD:0.19;95% CI,0.05 - 0.34;P = 0.01)、股骨颈[均值差(MD):0.01;95% CI,0.00 - 0.02;P = 0.04]、Ward三角区(MD:0.02;95% CI,0.01 - 0.04;P = 0.001)和大转子(MD:0.03;95% CI,0.02 - 0.04;P < 0.00001)在内的几块骨骼中产生更高的矿物质密度,高于不饮茶组。
这项荟萃分析提供了一个潜在趋势,即饮茶可能对骨密度有益,尤其是在腰椎、髋部、股骨颈、Ward三角区和大转子,这可能有助于预防骨质流失。