Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China.
Chinese Academy of Medical Sciences, Beijing, China.
Osteoporos Int. 2019 Feb;30(2):333-341. doi: 10.1007/s00198-018-4767-3. Epub 2018 Nov 15.
Tea is a worldwide drink with controversial effect on bone health. The sex-specific associations are unrevealed among general population. This study showed that prolonged moderate tea consumption benefited bone health in women, while no additional benefit with stronger tea. However, tea consumption was not associated with bone health in men.
Tea consumption has been shown a potentially beneficial effect on bone health in postmenopausal women. However, little is known about such association in men, and whether stronger tea instead harms bone health due to elevated urinary excretion of calcium associated with caffeine in the tea. The aim of this study was to examine the association between various metrics of tea consumption and bone health.
The present study included 20,643 participants from the China Kadoorie Biobank (CKB), who have finished both baseline survey (2004-2008) and a re-survey (2013-2014). They were aged 38-86 years at re-survey. Tea consumption was self-reported at both baseline and re-survey. Bone mineral density (BMD) was measured using calcaneal quantitative ultrasound once at re-survey.
Compared with non-consumers, prolonged weekly tea consumers in women was associated with higher calcaneus BMD measures, with β (95% CI) of 0.98 (0.22, 1.74) for BUA, 4.68 (1.74, 7.61) for SOS, and 1.95 (0.81, 3.10) for SI. Among prolonged weekly tea consumers, no linear increase in BMD measures with the amount of tea leaves added was observed. The SOS and SI were higher in consumers with tea leaves 3.0-5.9 g/day than in those with < 3.0 g/day, but were reduced to non-significant for those with ≥ 6.0 g/day. Tea consumption was not associated with calcaneus BMD measures in men.
Prolonged moderate tea consumption benefited bone health in women but not in men. For stronger tea consumption with more tea leaves added, neither benefit nor harm to bone health was observed.
茶是一种在全世界范围内饮用的饮品，其对骨骼健康的影响颇具争议。一般人群中尚未揭示其性别特异性关联。本研究表明，长期适量饮茶有益于女性的骨骼健康，而饮茶量增加并无额外益处。然而，饮茶与男性的骨骼健康无关。
饮茶已被证明对绝经后妇女的骨骼健康有潜在的益处。然而，对于男性，人们对此知之甚少，而且由于茶中的咖啡因会增加尿液中钙的排泄，因此是否更浓的茶反而会损害骨骼健康也不得而知。本研究旨在研究各种饮茶指标与骨骼健康之间的关系。
本研究纳入了来自中国慢性病前瞻性研究（CKB）的 20643 名参与者，他们均完成了基线调查（2004-2008 年）和再调查（2013-2014 年）。他们在再调查时的年龄为 38-86 岁。饮茶情况在基线和再调查时均采用自我报告的方式进行。在再调查时，使用跟骨定量超声仪测量一次跟骨骨密度（BMD）。
与非饮茶者相比，女性中长期每周饮茶者的跟骨 BMD 测量值较高，BUA 的 β（95%CI）为 0.98（0.22，1.74），SOS 为 4.68（1.74，7.61），SI 为 1.95（0.81，3.10）。在长期每周饮茶者中，并未观察到随着添加的茶叶量的增加，BMD 测量值呈线性增加。与每天摄入茶叶量<3.0g 的人群相比，每天摄入茶叶量为 3.0-5.9g 的人群的 SOS 和 SI 更高，但每天摄入茶叶量≥6.0g 的人群的 SOS 和 SI 则降低至无统计学意义。饮茶与男性的跟骨 BMD 测量值无关。
长期适量饮茶有益于女性的骨骼健康，但对男性则无益。对于饮茶量增加且茶叶添加量更多的浓茶，既没有发现对骨骼健康有益，也没有发现有害。
