Nakada Hiroshi, Sakae Toshiro, LeGeros Racquel Z, LeGeros John P, Suwa Taketoshi, Numata Yasuko, Kobayashi Kihei
Dept. of Gnatho-Oral Prosthetic Rehabilitation, Nihon University School of Dentistry at Matsudo, Japan.
Implant Dent. 2007 Sep;16(3):281-9. doi: 10.1097/ID.0b013e3180e92a78.
It is now well known that implant surface properties affect osseointegration. Grit-blasting with abrasives and coating by plasma are methods to modify implant surfaces. This study aimed to compare the direction of new bone formation associated with three types of surfaces.
Titanium (Ti) alloy rods grit-blasted with alumina abrasive (Group 1, G1), with apatitic abrasive (Group 2, G2), and with apatitic abrasive and plasma-sprayed with hydroxyapatite (Group 3, G3) were implanted in surgically created defects in tibias of New Zealand white rabbits for 2 and 4 weeks. After sacrifice, the implants and surrounding bones were obtained and analyzed using back scattered imaging.
Differences in patterns of bone formation among the groups were observed: originating from the cortical bone towards the implant surface (Type A), surrounding the implant (Type B) and originating from the medullary cavity (Type C). G1 and G3 showed Types A and B while G2 exhibited Types A, B and C. After 4 weeks, greater amount of new bone was observed in G2 group compared with those in G1 and G3 groups.
This study demonstrated that patterns of bone formation are influenced by methods of surface modification.
目前众所周知，种植体表面特性会影响骨结合。用磨料喷砂和等离子涂层是改变种植体表面的方法。本研究旨在比较与三种类型表面相关的新骨形成方向。
将用氧化铝磨料喷砂的钛（Ti）合金棒（第1组，G1）、用磷灰石磨料喷砂的（第2组，G2）以及用磷灰石磨料喷砂并等离子喷涂羟基磷灰石的（第3组，G3）植入新西兰白兔胫骨手术造成的缺损中2周和4周。处死后，获取种植体和周围骨骼，并用背散射成像进行分析。
观察到各组之间骨形成模式的差异：从皮质骨向种植体表面起源（A型）、围绕种植体（B型）以及从髓腔起源（C型）。G1和G3显示出A型和B型，而G2表现出A型、B型和C型。4周后，与G1和G3组相比，G2组观察到更多的新骨。
本研究表明骨形成模式受表面改性方法的影响。
