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静脉药物成瘾者的血管血栓性肺肉芽肿病

[Angiothrombotic pulmonary granulomatosis in intravenous drug addicts].

作者信息

Pintado V, Valencia M E, Lavilla P, López-Duplá J M, Llanos C, Gil A

机构信息

Servicio de Medicina Interna, Universidad Autónoma, Madrid.

出版信息

Rev Clin Esp. 1991 Apr;188(7):362-4.

PMID:1784766
Abstract

Two cases of angio-thrombotic lung granulomatosis in intravenous drug addicts are described. This entity has been previously described in drug addicts who inject oral drugs intravenously. Talc, which is used in the preparation of several drugs, cotton and other substances provoke at lung vessels level, thrombotic phenomena with strange body granuloma formations. Depending on the predominating localization of these lesions, interstitial pneumonia or pulmonary hypertension can later occur, such is the case in one of our patients who had a fatal evolution in a short period of time.

摘要

本文描述了两例静脉注射吸毒者发生的血管血栓性肺肉芽肿病。此前曾在静脉注射口服药物的吸毒者中描述过这种病症。用于多种药物制剂中的滑石粉、棉花及其他物质,在肺血管层面引发血栓形成现象,并伴有奇异的异物肉芽肿形成。根据这些病变的主要部位,随后可能会发生间质性肺炎或肺动脉高压,我们的一名患者就是如此,其在短时间内病情恶化并死亡。

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