Daniels P W, Halpin K, Hyatt A, Middleton D
CSIRO Livestock Industries, Australian Animal Health Laboratory, Geelong, Australia.
Curr Top Microbiol Immunol. 2007;315:113-31. doi: 10.1007/978-3-540-70962-6_6.
Infection and disease in reservoir and spillover hosts determine patterns of infectious agent availability and opportunities for infection, which then govern the process of transmission between susceptible species. In this chapter, using the zoonotic agents Hendra virus and Nipah virus as examples, the pathogenesis of infection in various species including the wildlife reservoirs and domestic spillover hosts is reviewed with an emphasis on the aspects of pathogenesis which contribute to the dissemination of infection. Through these discussions, the emergence of these zoonotic agents is explored.
储存宿主和溢出宿主中的感染与疾病决定了传染源的可获得性模式以及感染机会，进而控制了易感物种之间的传播过程。在本章中，以亨德拉病毒和尼帕病毒这些人畜共患病病原体为例，回顾了包括野生动物储存宿主和家养溢出宿主在内的各种物种的感染发病机制，重点关注有助于感染传播的发病机制方面。通过这些讨论，探究了这些人畜共患病病原体的出现情况。
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