Diagnostic Medicine/Pathobiology Department, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA.
Zoonoses Public Health. 2012 Sep;59 Suppl 2(Suppl 2):2-31. doi: 10.1111/j.1863-2378.2012.01539.x.
The 6th International Conference on Emerging Zoonoses, held at Cancun, Mexico, 24-27 February 2011, offered 84 participants from 18 countries, a snapshot of current research in numerous zoonoses caused by viruses, bacteria or prions. Co-chaired by Professors Heinz Feldmann and Jürgen Richt, the conference explored 10 topics: (i) The ecology of emerging zoonotic diseases; (ii) The role of wildlife in emerging zoonoses; (iii) Cross-species transmission of zoonotic pathogens; (iv) Emerging and neglected influenza viruses; (v) Haemorrhagic fever viruses; (vi) Emerging bacterial diseases; (vii) Outbreak responses to zoonotic diseases; (viii) Food-borne zoonotic diseases; (ix) Prion diseases; and (x) Modelling and prediction of emergence of zoonoses. Human medicine, veterinary medicine and environmental challenges are viewed as a unity, which must be considered under the umbrella of 'One Health'. Several presentations attempted to integrate the insights gained from field data with mathematical models in the search for effective control measures of specific zoonoses. The overriding objective of the research presentations was to create, improve and use the tools essential to address the risk of contagions in a globalized society. In seeking to fulfil this objective, a three-step approach has often been applied: (i) use cultured cells, model and natural animal hosts and human clinical models to study infection; (ii) combine traditional histopathological and biochemical approaches with functional genomics, proteomics and computational biology; and (iii) obtain signatures of virulence and insights into mechanisms of host defense response, immune evasion and pathogenesis. This meeting review summarizes 39 of the conference presentations and mentions briefly the 16 articles in this Special Supplement, most of which were presented at the conference in earlier versions. The full affiliations of all presenters and many colleagues have been included to facilitate further inquiries from readers.
第六届新发传染病国际会议于 2011 年 2 月 24 日至 27 日在墨西哥坎昆举行，来自 18 个国家的 84 名代表参加了会议，会议展示了目前在病毒、细菌或朊病毒引起的多种人畜共患病研究领域的最新成果。会议由 Heinz Feldmann 教授和 Jürgen Richt 教授共同主持，探讨了 10 个主题：（i）新发人畜共患病的生态学；（ii）野生动物在新发人畜共患病中的作用；（iii）人畜共患病病原体的跨物种传播；（iv）新发和被忽视的流感病毒；（v）出血热病毒；（vi）新发细菌性疾病；（vii）对人畜共患病的暴发应对；（viii）食源性病原体；（ix）朊病毒病；（x）人畜共患病出现的建模与预测。人医、兽医和环境挑战被视为一个整体，必须在“同一健康”的框架下加以考虑。有几个专题介绍尝试将实地数据与数学模型相结合，以寻找针对特定人畜共患病的有效控制措施。研究专题的首要目标是创建、改进和使用应对全球化社会传染病风险的必要工具。为了实现这一目标，经常采用三步方法：（i）使用培养细胞、模型和天然动物宿主以及人类临床模型来研究感染；（ii）将传统的组织病理学和生物化学方法与功能基因组学、蛋白质组学和计算生物学相结合；（iii）获得毒力特征和宿主防御反应、免疫逃避和发病机制的见解。本会议综述总结了会议的 39 个专题介绍，并简要提及本期特刊中的 16 篇文章，其中大多数在会议上以较早版本进行了介绍。所有发言者和许多同事的完整联系方式都已列出，方便读者进一步咨询。
