硅金属及合金的生产与肺功能加速衰退有关：一项针对挪威冶炼厂3924名员工的5年前瞻性研究。
Production of silicon metal and alloys is associated with accelerated decline in lung function: a 5-year prospective study among 3924 employees in norwegian smelters.
作者信息
Søyseth Vidar, Johnsen Helle Laier, Benth Jūrate Saltyte, Hetland Siri Merete, Kongerud Johny
机构信息
Department of Medicine, Faculty Division, Akershus University Hospital, University of Oslo, N-1478 Lørenskog, Norway.
出版信息
J Occup Environ Med. 2007 Sep;49(9):1020-6. doi: 10.1097/JOM.0b013e3181452830.
OBJECTIVES
To investigate the association between decline in lung function and production of alloys in the Norwegian smelting industry.
METHODS
All employees (N = 3924) were examined annually for 5 years (16,570 examinations). The employees were classified into three categories: 1) line operators (employed full time in the production line), 2) nonexposed (no exposure last year), and 3) non-line operators (remaining subjects). The outcome variable was expressed as forced expiratory volume in 1 second per squared height (FEV1/height(2)).
RESULTS
In the subcohorts of the ferrosilicon/silicon metal and silicon carbide industries, the differences between line operators and nonexposed workers were -2.3 (-4.3 to -0.3) (CI = 95%) and -5.6 (-10.4 to -0.7) mL/(m(2) x year), respectively.
CONCLUSION
Line operators in the ferrosilicon/silicon metal and silicon carbide industries had a steeper annual decline in FEV1/height compared with nonexposed workers.
目的
研究挪威冶炼行业肺功能下降与合金生产之间的关联。
方法
对所有员工（N = 3924）进行了为期5年的年度检查（共16570次检查）。员工被分为三类：1）生产线操作员（在生产线全职工作），2）未暴露者（去年无暴露），3）非生产线操作员（其余受试者）。结果变量表示为每平方米身高的1秒用力呼气量（FEV1/身高²）。
结果
在硅铁/金属硅和碳化硅行业的亚队列中，生产线操作员与未暴露工人之间的差异分别为-2.3（-4.3至-0.3）（CI = 95%）和-5.6（-10.4至-0.7）mL/（m²×年）。
结论
与未暴露工人相比，硅铁/金属硅和碳化硅行业的生产线操作员的FEV1/身高年下降幅度更大。
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