铝电解车间工人的用力呼气量年下降幅度比未接触车间烟雾的工人更大。
Annual decline in forced expiratory volume is steeper in aluminum potroom workers than in workers without exposure to potroom fumes.
作者信息
Søyseth Vidar, Henneberger Paul K, Einvik Gunnar, Virji Mohammed Abbas, Bakke Berit, Kongerud Johny
机构信息
Medical Division, Akershus University Hospital, Lørenskog, Norway.
Faculty of Medicine, University of Oslo, Oslo, Norway.
出版信息
Am J Ind Med. 2016 Apr;59(4):322-9. doi: 10.1002/ajim.22570. Epub 2016 Feb 8.
BACKGROUND
Aluminum potroom exposure is associated with increased mortality of COPD but the association between potroom exposure and annual decline in lung function is unknown. We have measured lung volumes annually using spirometry from 1986 to 1996. The objective was to compare annual decline in forced expiratory volume in 1 s (dFEV1) and forced vital capacity (dFVC).
METHODS
The number of aluminum potroom workers was 4,546 (81% males) and the number of workers in the reference group was 651 (76% males). The number of spirometries in the index group and the references were 24,060 and 2,243, respectively.
RESULTS
After adjustment for confounders, the difference in dFEV1 and dFVC between the index and reference groups were 13.5 (P < 0.001) and -8.0 (P = 0.060) ml/year.
CONCLUSION
Aluminum potroom operators have increased annual decline in FEV1 relative to a comparable group with non-exposure to potroom fumes and gases.
背景
铝电解车间暴露与慢性阻塞性肺疾病（COPD）死亡率增加有关，但电解车间暴露与肺功能年度下降之间的关联尚不清楚。我们在1986年至1996年期间每年使用肺活量测定法测量肺容量。目的是比较1秒用力呼气容积（dFEV1）和用力肺活量（dFVC）的年度下降情况。
方法
铝电解车间工人有4546名（81%为男性），参照组工人有651名（76%为男性）。指数组和参照组的肺活量测定次数分别为24060次和2243次。
结果
在对混杂因素进行校正后，指数组与参照组之间dFEV1和dFVC的差异分别为每年13.5（P<0.001）和-8.0（P=0.060）ml。
结论
与未接触电解车间烟雾和气体的可比组相比，铝电解车间工人的FEV1年度下降有所增加。
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