Purice S, Serban M G, Negru T
N. Gh. Lupu Institute of Internal Medicine, Bucharest, Romania.
Rom J Intern Med. 1991 Jul-Dec;29(3-4):145-9.
In a group of 75 patients with collagen diseases a study was carried out for the structural characterization of the circulating immune complexes (CIC) and the eventual detection of a correlation between these complexes and various serum biologic parameters. The results obtained have demonstrated: (a) the great variability of the structure of immune complexes even in the same type of disease and (b) the lack of correlation between the concentration of components in the CIC structure and the level of the same components in the serum. The lack of correlation may be explained by the great variety of immune complexes formation and the increase of any of the serum immunoglobulins does not necessarily mean its total or partial aggregation in the CIC structure.
在一组75例胶原病患者中，对循环免疫复合物（CIC）的结构特征进行了研究，并最终检测了这些复合物与各种血清生物学参数之间的相关性。所获得的结果表明：（a）即使在同一类型的疾病中，免疫复合物的结构也存在很大差异；（b）CIC结构中各成分的浓度与血清中相同成分的水平之间缺乏相关性。这种缺乏相关性可能是由于免疫复合物形成的多样性很大，血清中任何一种免疫球蛋白的增加并不一定意味着它在CIC结构中完全或部分聚集。
