Lee Ching-Chih, Ho Hsu-Chueh, Chen Huang-Li, Hsiao Shih-Hsuan, Hwang Juen-Haur, Hung Shih-Kai
Department of Otolaryngology, Buddhist Dalin Tzu Chi General Hospital, 2, Ming Shen Road, Dalin, Chiayi, 622, Taiwan.
Acta Otolaryngol. 2007 Nov;127(11):1214-7. doi: 10.1080/00016480701230910.
Young patients with squamous cell carcinoma (SCC) of the oral tongue developed fewer locoregional recurrences. The overall survival and disease-specific survival rates were better in the young patient population.
To compare the survival rates of patients under 45 years of age and diagnosed with SCC of the oral tongue with those of patients older than 45 years.
A retrospective review of 20 patients under 45 years of age with SCC of the oral tongue was performed. These patients were matched to an older population by sex and clinical stage. Overall survival, disease-free survival, disease-specific survival, and rates of local, regional and distant metastases were determined for both populations.
Stage and treatment modality were similar in the two age groups. There were significant differences in overall survival (p=0.013) and disease-specific survival (p=0.046) favoring young patients. Rates of locoregional recurrence and distant metastasis were higher in the older patients.
年轻的舌鳞状细胞癌（SCC）患者局部区域复发较少。年轻患者群体的总生存率和疾病特异性生存率更高。
比较45岁以下诊断为舌鳞状细胞癌的患者与45岁以上患者的生存率。
对20例45岁以下的舌鳞状细胞癌患者进行回顾性研究。这些患者按性别和临床分期与年龄较大的人群进行匹配。确定了两组人群的总生存率、无病生存率、疾病特异性生存率以及局部、区域和远处转移率。
两个年龄组的分期和治疗方式相似。年轻患者在总生存率（p = 0.013）和疾病特异性生存率（p = 0.046）方面存在显著差异。老年患者的局部区域复发率和远处转移率更高。
