布鲁内因A - C，来自褐丝膜菌的β-咔啉生物碱。
Brunneins A-C, beta-carboline alkaloids from Cortinarius brunneus.
作者信息
Teichert Axel, Schmidt Jürgen, Porzel Andrea, Arnold Norbert, Wessjohann Ludger
机构信息
Department of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, D-06120 Halle/Saale, Germany.
出版信息
J Nat Prod. 2007 Sep;70(9):1529-31. doi: 10.1021/np070259w. Epub 2007 Sep 14.
Four beta-carboline alkaloids, brunneins A-C (1-3) and 3-(7-hydroxy-9H-beta-carboline-1-yl)propanoic acid (4), were isolated from fruiting bodies of the agaricoid fungus Cortinarius brunneus. The structures of 1-3 were determined by analysis of NMR and MS data, and the structure of compound 4 was determined by comparison with published data. Brunnein A (1) exhibited very low cholinesterase inhibitory effects and no cytotoxicity.
从伞菌状真菌褐丝膜菌的子实体中分离出四种β-咔啉生物碱，即褐丝膜菌素A-C（1-3）和3-（7-羟基-9H-β-咔啉-1-基）丙酸（4）。通过核磁共振（NMR）和质谱（MS）数据分析确定了1-3的结构，化合物4的结构则通过与已发表数据进行比较得以确定。褐丝膜菌素A（1）表现出极低的胆碱酯酶抑制作用且无细胞毒性。
Zotero 插件