波斯阿魏草根的极性次生代谢产物。

Polar secondary metabolites of Ferula persica roots.

作者信息

Iranshahi Mehrdad, Mojarab Mehdi, Sadeghian Hamid, Hanafi-Bojd Mohammad Yahya, Schneider Bernd

机构信息

Department of Pharmacognosy and Biotechnology, Biotechnology Research Center, Faculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Phytochemistry. 2008 Jan;69(2):473-8. doi: 10.1016/j.phytochem.2007.08.001. Epub 2007 Sep 12.

DOI:10.1016/j.phytochem.2007.08.001

PMID:17854851

Abstract

Phytochemical investigation of the methanolic extract of the dried roots of Ferula persica resulted in four sesquiterpene coumarin glycosides, persicaosides A-D, and two known phytosterol glucosides, sitosterol 3-O-beta-glucoside and stigmasterol 3-O-beta-glucoside. The structures of these compounds were elucidated by extensive spectroscopic methods including 1D-((1)H and (13)C) and 2D NMR experiments (DQF-COSY, HSQC, HMBC, and ROESY) as well as ESIMS and TOFMS analyses.

摘要

对波斯阿魏干根甲醇提取物进行植物化学研究，得到了四种倍半萜香豆素苷，即波斯阿魏苷A - D，以及两种已知的植物甾醇苷，即β-谷甾醇3 - O - β -葡萄糖苷和豆甾醇3 - O - β -葡萄糖苷。通过广泛的光谱方法，包括一维（¹H和¹³C）和二维核磁共振实验（DQF - COSY、HSQC、HMBC和ROESY）以及电喷雾离子化质谱（ESIMS）和飞行时间质谱（TOFMS）分析，阐明了这些化合物的结构。