Kumar S, Kumar D, Deshmukh R R, Lokhande P D, More S N, Rangari V D
Department of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra-136119, Haryana, India.
Fitoterapia. 2008 Jan;79(1):21-3. doi: 10.1016/j.fitote.2007.06.012. Epub 2007 Aug 11.
The plant Phyllanthus reticulatus is claimed to have antidiabetic activity in tribal area. To validate the tribal claim, the petroleum ether and ethanolic extracts of leaves of the P. reticulatus were orally tested at 500 and 1000 mg/kg for hypoglycemic effect in alloxan induces diabetic mice. It shows antidiabetic activity at the dose of 1000 mg/kg. The phytochemical screening of the residues revealed the presence of terpenoids glycosides, protein, carbohydrates and absence of alkaloids and steroids.
在部落地区，人们称网脉叶下珠植物具有抗糖尿病活性。为验证部落的这一说法，对网脉叶下珠叶子的石油醚提取物和乙醇提取物进行了口服测试，在给四氧嘧啶诱导的糖尿病小鼠分别喂食500毫克/千克和1000毫克/千克剂量后，观察其降血糖效果。结果显示，在1000毫克/千克的剂量下该提取物具有抗糖尿病活性。对提取物残渣进行的植物化学筛选表明，其中存在萜类糖苷、蛋白质、碳水化合物，且不含生物碱和类固醇。
