King A, Loke Y W
Dept of Pathology, Cambridge University, UK.
Immunol Today. 1991 Dec;12(12):432-5. doi: 10.1016/0167-5699(91)90014-K.
The 'foetal allograft' concept of the maternal-foetal relationship is currently being questioned. This is partly due to the increasing awareness of uterine large granular lymphocytes, a subset of natural killer cells found in the human endometrium at the time of placentation. Analogous cells are present in several species. The possible role of these cells in the regulation of the trophoblast-maternal interface is discussed here by Ashley King and Yung Wai Loke.
母婴关系的“胎儿同种异体移植”概念目前正受到质疑。部分原因是人们越来越认识到子宫大颗粒淋巴细胞,这是一种在胎盘形成时存在于人类子宫内膜中的自然杀伤细胞亚群。类似的细胞在几个物种中都有存在。阿什利·金和容·韦·洛克在此讨论了这些细胞在调节滋养层与母体界面中的可能作用。