Wade Tracey D, Gillespie Nathan, Martin Nicholas G
School of Psychology, Flinders University, Adelaide, South Australia, Australia.
Int J Eat Disord. 2007 Dec;40(8):679-86. doi: 10.1002/eat.20461.
To investigate the differential profile of early family life events associated with lifetime anorexia nervosa (AN), bulimia nervosa (BN), and major depression (MD).
Only data from the monozygotic twins (n = 622) were examined from a community sample of female twins who had participated in three waves of data collection. Eating disorder and MD diagnoses were ascertained from the Eating Disorder Examination at Wave 3 and interview at Wave 2 respectively. Early family events were ascertained from self-report measures at Waves 1 and 3. Two case control designs were used, including a comparison of women: (1) who had lifetime AN, BN, MD, and controls, and (2) twin pairs discordant for either AN, BN, or MD (where the unaffected cotwin formed the control group).
Across the two types of designs, compared to controls, both AN and BN were associated with more comments from the family about weight and shape when growing up. AN was uniquely associated with higher levels of paternal protection while BN was associated with higher levels of parental expectations.
While some overlap among early life events was indicated, especially related to parental conflict and criticism, there was evidence to support some degree of nonoverlap among life events associated with AN, BN, and MD.
调查与终生神经性厌食症（AN）、神经性贪食症（BN）和重度抑郁症（MD）相关的早期家庭生活事件的差异特征。
仅对参与了三轮数据收集的女性双胞胎社区样本中的同卵双胞胎（n = 622）的数据进行检查。分别根据第三轮的饮食失调检查和第二轮的访谈确定饮食失调和MD诊断。早期家庭事件通过第一轮和第三轮的自我报告测量来确定。使用了两种病例对照设计，包括对女性的比较：（1）患有终生AN、BN、MD的女性与对照组，以及（2）在AN、BN或MD方面不一致的双胞胎对（其中未受影响的双胞胎形成对照组）。
在两种设计类型中，与对照组相比，AN和BN在成长过程中都与来自家庭更多关于体重和体型的评论相关。AN与更高水平的父亲保护独特相关，而BN与更高水平的父母期望相关。
虽然表明早期生活事件之间存在一些重叠，特别是与父母冲突和批评有关，但有证据支持与AN、BN和MD相关的生活事件在一定程度上不重叠。
