Mazzeo Suzanne E, Bulik Cynthia M
Departments of Psychology and Pediatrics, Virginia Commonwealth University, 806 West Franklin Street, Richmond, VA 23284-2018, USA.
Child Adolesc Psychiatr Clin N Am. 2009 Jan;18(1):67-82. doi: 10.1016/j.chc.2008.07.003.
Patients and families often are aware of research on genetic factors influencing eating disorders. Accurate interpretations of research on environmental and genetic risk factors can be empowering to patients and families; however, misinterpretations could prove detrimental. Clinicians who are not versed in genetic research may believe they are ill prepared to discuss the nuances of genetic research with patients and families. In this article the authors discuss what is known about genetic and environmental risk factors with an emphasis on gene-environment interplay to improve clinicians' comfort level in discussing these complex issues with their patients.
患者及其家属通常了解有关影响饮食失调的遗传因素的研究。对环境和遗传风险因素研究的准确解读可以增强患者及其家属的信心;然而,错误解读可能会造成损害。不熟悉基因研究的临床医生可能认为自己没有做好准备与患者及其家属讨论基因研究的细微差别。在本文中,作者讨论了已知的遗传和环境风险因素,重点是基因-环境相互作用,以提高临床医生在与患者讨论这些复杂问题时的舒适度。