一名银屑病患者出现酷似银屑病的米贝利巨大疣状汗孔角化症。

Giant verrucous porokeratosis of Mibelli mimicking psoriasis in a patient with psoriasis.

作者信息

De Simone Clara, Paradisi Andrea, Massi Guido, Proietti Ilaria, Capponi Angela, Amerio Pier Luigi, Capizzi Rodolfo

机构信息

Department of Dermatology, Università Cattolica del Sacro Cuore, Rome, Italy.

出版信息

J Am Acad Dermatol. 2007 Oct;57(4):665-8. doi: 10.1016/j.jaad.2007.03.020.

DOI:10.1016/j.jaad.2007.03.020

PMID:17870431

Abstract

Porokeratosis of Mibelli is a disorder of epidermal keratinization characterized by annular plaques with an atrophic center surrounded by a keratotic wall. We report a case of a giant verrucous porokeratosis of Mibelli mimicking psoriasis that developed in a patient with psoriasis and therefore went unrecognized for a long time. Histologically the lesion combined features of porokeratosis at the periphery and of psoriasis at its center, a picture recently described as "psoriasis encircled by porokeratosis." The possible pathogenetic relationship between psoriasis and the development of porokeratosis is also discussed.

摘要

米贝利汗孔角化症是一种表皮角化异常疾病，其特征为环形斑块，中央萎缩，周围有角化性边缘。我们报告一例巨大疣状米贝利汗孔角化症病例，该病例酷似银屑病，发生于一名银屑病患者，因此长期未被识别。组织学上，病变在外周具有汗孔角化症特征，在中央具有银屑病特征，这种表现最近被描述为“汗孔角化症环绕银屑病”。本文还讨论了银屑病与汗孔角化症发生之间可能的发病机制关系。