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[米贝利汗孔角化症的疣状变体作为寻常型银屑病的鉴别诊断]

[Verrucous variant of porokeratosis of Mibelli as a differential diagnosis of psoriasis vulgaris].

作者信息

Wagner G, Meyer V, Sachse M M

机构信息

Klinik für Dermatologie, Allergologie und Phlebologie, Klinikum Bremerhaven Reinkenheide, Bremerhaven, Postbrookstr. 103, 27574, Bremerhaven, Deutschland.

出版信息

Hautarzt. 2016 Mar;67(3):244-8. doi: 10.1007/s00105-015-3720-z.

DOI:10.1007/s00105-015-3720-z
PMID:26525967
Abstract

In a 37-year-old man, diagnosis of verrucous porokeratosis could only be made by histological examination. Previously, the skin lesions on the right buttock had been treated by several dermatologists as psoriasis vulgaris. The clinical picture of both dermatoses was characterized by sharply defined, erythematous papules and plaques. Precise evaluation of the clinical morphology was key for diagnosis. Moreover, in contrast to psoriasis, verrucous porokeratosis is characterized by a high degree of treatment resistance.

摘要

在一名37岁男性中,疣状汗孔角化症只能通过组织学检查来确诊。此前,右臀部的皮肤病变被几位皮肤科医生当作寻常型银屑病进行治疗。这两种皮肤病的临床表现均以边界清晰的红斑丘疹和斑块为特征。对临床形态的精确评估是诊断的关键。此外,与银屑病不同,疣状汗孔角化症的特点是具有高度的治疗抵抗性。

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[77-year-old female with persisting erythematous and scaly plaques on the extremities and upper trunk : Preparation for the medical specialist examination: Part 20].[77岁女性,四肢及上躯干有持续性红斑鳞屑性斑块:医学专科检查准备:第20部分]
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本文引用的文献

1
Porokeratosis ptychotropica: a rare variant of porokeratosis.向心性汗孔角化症:汗孔角化症的一种罕见变异型。
Dermatol Online J. 2014 Jun 15;20(6):13030/qt26d5p9v7.
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Disseminated giant hyperkeratotic porokeratosis and treatment with acitretin: a case report.
Acta Derm Venereol. 2015 Feb;95(2):241-2. doi: 10.2340/00015555-1908.
3
Porokeratosis of Mibelli--literature review and a case report.米贝利汗孔角化症——文献综述及病例报告
An Bras Dermatol. 2013 Nov-Dec;88(6 Suppl 1):179-82. doi: 10.1590/abd1806-4841.20132721.
4
Porokeratosis ptychotropica: a rare and evolving variant of porokeratosis.向心性汗孔角化症:一种罕见且不断演变的汗孔角化症变体。
J Cutan Pathol. 2013 Dec;40(12):1042-7. doi: 10.1111/cup.12233. Epub 2013 Oct 12.
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Identification of an interstitial 18p11.32-p11.31 duplication including the EMILIN2 gene in a family with porokeratosis of Mibelli.鉴定一个包含 EMILIN2 基因的 18p11.32-p11.31 号染色体间插性重复序列,该重复序列存在于一个患有米贝利氏脓疱性角化病的家族中。
PLoS One. 2013 Apr 10;8(4):e61311. doi: 10.1371/journal.pone.0061311. Print 2013.
6
Porokeratosis: present concepts.角化病:现有概念。
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Extramammary Paget disease - clinical appearance, pathogenesis, management.乳房外 Paget 病——临床表现、发病机制、治疗。
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8
Verrucous porokeratosis of the gluteal cleft (porokeratosis ptychotropica): a rare disorder easily misdiagnosed.臀沟疣状汗孔角化症(向褶性汗孔角化症):一种易被误诊的罕见病症。
J Cutan Pathol. 2010 Jul;37(7):802-7. doi: 10.1111/j.1600-0560.2009.01387.x. Epub 2009 Jul 21.
9
Verrucous porokeratosis of Mibelli on the buttocks mimicking psoriasis.臀部米贝利氏疣状汗孔角化症,酷似银屑病。
Cutis. 2003 Nov;72(5):391-3.
10
The hyperkeratotic variant of porokeratosis Mibelli is a distinct entity: clinical and ultrastructural evidence.米贝利汗孔角化症的角化过度型是一种独特的病症:临床及超微结构证据
Dermatology. 1996;192(3):255-8. doi: 10.1159/000246378.