Faith Jeremiah J, Olson Andrew J, Gardner Timothy S, Sachidanandam Ravi
Bioinformatics Program, Boston University, USA.
BMC Bioinformatics. 2007 Sep 18;8:344. doi: 10.1186/1471-2105-8-344.
Lightweight genome viewer (lwgv) is a web-based tool for visualization of sequence annotations in their chromosomal context. It performs most of the functions of larger genome browsers, while relying on standard flat-file formats and bypassing the database needs of most visualization tools. Visualization as an aide to discovery requires display of novel data in conjunction with static annotations in their chromosomal context. With database-based systems, displaying dynamic results requires temporary tables that need to be tracked for removal.
lwgv simplifies the visualization of user-generated results on a local computer. The dynamic results of these analyses are written to transient files, which can import static content from a more permanent file. lwgv is currently used in many different applications, from whole genome browsers to single-gene RNAi design visualization, demonstrating its applicability in a large variety of contexts and scales.
lwgv provides a lightweight alternative to large genome browsers for visualizing biological annotations and dynamic analyses in their chromosomal context. It is particularly suited for applications ranging from short sequences to medium-sized genomes when the creation and maintenance of a large software and database infrastructure is not necessary or desired.
轻量级基因组浏览器（lwgv）是一种基于网络的工具，用于在染色体背景下可视化序列注释。它执行大多数大型基因组浏览器的功能，同时依赖于标准的平面文件格式，绕过了大多数可视化工具对数据库的需求。作为发现辅助手段的可视化需要在染色体背景下将新数据与静态注释结合显示。对于基于数据库的系统，显示动态结果需要跟踪以便删除临时表。
lwgv简化了在本地计算机上对用户生成结果的可视化。这些分析的动态结果被写入临时文件，临时文件可以从更持久的文件中导入静态内容。lwgv目前被用于许多不同的应用，从全基因组浏览器到单基因RNAi设计可视化，证明了其在各种背景和规模下的适用性。
lwgv为在染色体背景下可视化生物学注释和动态分析提供了一种轻量级的大型基因组浏览器替代方案。当不需要或不希望创建和维护大型软件和数据库基础设施时，它特别适用于从短序列到中等规模基因组的应用。
