Wang Hui, Ooi Engchoon Vincent, Ang Put O
Medical College, Jinan University, Guangzhou 510632, China.
Sci China C Life Sci. 2007 Oct;50(5):611-8. doi: 10.1007/s11427-007-0086-1.
Two relatively pure polysaccharides H3-a1 and H3-b1 had been isolated from the brown seaweed Hydroclathrus clathratus. They were characterized by HPLC, ultraviolet scanning, gas chromatography, infrared spectroscopy and elemental analysis, and shown to be two different sulfated polysaccharides with different monosaccharide content, but both with high relative molecular mass. They contained some proteins and uronic acid respectively. The sulfate content and bioactivity of these polysaccharides varied during purification. The fractions derived from the hot water extract also exhibited low anticoagulant effect. This is the first time that the antiherpetic and anticoagulant activities were evaluated for the polysaccharides from the Hong Kong brown seaweed Hydroclathrus clathratus.
从褐藻水云（Hydroclathrus clathratus）中分离出了两种相对纯净的多糖H3-a1和H3-b1。通过高效液相色谱法（HPLC）、紫外扫描、气相色谱法、红外光谱法和元素分析对它们进行了表征，结果表明它们是两种不同的硫酸化多糖，单糖含量不同，但相对分子质量都很高。它们分别含有一些蛋白质和糖醛酸。这些多糖在纯化过程中硫酸根含量和生物活性有所变化。热水提取物得到的级分也表现出较低的抗凝作用。这是首次对来自香港褐藻水云（Hydroclathrus clathratus）的多糖进行抗疱疹和抗凝活性评估。
