Ouyang Ann, Xu Lihua
H045, Division of Gastroenterology and Hepatology, The Milton S. Hershey Medical Center, 500 University Drive, Hershey, PA 17033, United States.
World J Gastroenterol. 2007 Oct 28;13(40):5360-6. doi: 10.3748/wjg.v13.i40.5360.
To evaluate the effectiveness of a holistic acupuncture approach on nausea, pain, bloating and electrogastrogram (EGG) parameters in patients with intractable symptoms.
Twelve patients with no or mild nausea (those without nausea had bloating or pain) and 10 with a history of moderate to severe nausea were referred for acupuncture. All underwent an EGG and were treated at acupuncture points PC6, SP4 and DU20. Visual analog scales (VAS) assessing severity of nausea, pain and bloating were obtained before and after acupuncture treatment. Nineteen patients received three and three patients received two treatments.
VAS scores for nausea reflected the clinical assessment and differed significantly between mild and moderate/severe nausea groups. Acupuncture significantly improved severity of nausea in both groups with improved pre-treatment nausea between the first and third treatments in the moderate/severe nausea group. Pain scores improved with acupuncture in the mild nausea group only and bloating improved only with the first treatment in this group. Patients with bloating with VAS scores greater than 35 pre-treatment improved with acupuncture and over all VAS scores for pain improved with treatment. Acupuncture increased the power in the 2.7 to 3.5 cpm range in the EGG.
In this uncontrolled clinical study, a holistic acupuncture approach significantly improved nausea in patients with refractory symptoms and increased the power in the 2.7-3.5 cpm component of the electrogastrogram. Bloating and pain VAS scores improved acutely with treatment. This study suggests that acupuncture may be effective in this refractory group of patients and further study using appropriate controls is warranted.
评估整体针刺疗法对难治性症状患者恶心、疼痛、腹胀及胃电图(EGG)参数的疗效。
12例无恶心或轻度恶心(无恶心者有腹胀或疼痛)的患者以及10例有中度至重度恶心病史的患者被转诊接受针刺治疗。所有患者均接受了胃电图检查,并在穴位内关(PC6)、公孙(SP4)和百会(DU20)进行治疗。在针刺治疗前后获取视觉模拟量表(VAS)以评估恶心、疼痛和腹胀的严重程度。19例患者接受了3次治疗,3例患者接受了2次治疗。
恶心的VAS评分反映了临床评估结果,轻度和中度/重度恶心组之间存在显著差异。针刺显著改善了两组患者的恶心严重程度,中度/重度恶心组在第一次和第三次治疗之间预处理恶心情况有所改善。仅轻度恶心组的疼痛评分经针刺后有所改善,且该组仅在第一次治疗后腹胀情况有所改善。预处理时VAS评分大于35的腹胀患者经针刺后有所改善,总体疼痛VAS评分经治疗后有所改善。针刺增加了胃电图中2.7至3.5次/分钟范围内的功率。
在这项非对照临床研究中,整体针刺疗法显著改善了难治性症状患者的恶心情况,并增加了胃电图中2.7 - 3.5次/分钟成分的功率。治疗后腹胀和疼痛的VAS评分迅速改善。本研究表明针刺可能对此类难治性患者有效,有必要采用适当对照进行进一步研究。