Stepanova E I, Chaialo P P, Kolpakov I E, Kondrashova V G, Kurilo L V, Galichanskaia T Ia, Fediakova O B, Ivaniuk A G
Pediatriia. 1991(12):8-13.
Overall 1580 children from the regions with unsafe radiation situation were examined comprehensively at different times after the accident. The data obtained were correlated to the results of examining 610 children of the control group. The basic group children manifested a higher incidence of diverse alterations on the part of many organs and systems, which was accompanied by an increase of free radical processes signs of destabilization of cellular membranes, activation of blood cell metabolism, suppression of the T cell component of immunity in the presence of vegetovascular dysfunction. A tendency was noted toward normalization of these alterations seen over time after the accident. No clear-cut dose-effect dependence was found.
总体而言,对事故发生后不同时间来自辐射不安全地区的1580名儿童进行了全面检查。将获得的数据与对照组610名儿童的检查结果进行了关联。基础组儿童在许多器官和系统方面出现各种改变的发生率较高,同时伴有自由基过程迹象增加、细胞膜稳定性破坏、血细胞代谢激活、在存在植物神经血管功能障碍的情况下免疫T细胞成分受到抑制。注意到事故发生后的一段时间内这些改变有趋于正常化的趋势。未发现明确的剂量效应依赖性。