Setacci C, Chisci E, de Donato G, Setacci F, Sirignano P, Galzerano G
Department of Surgery, Vascular and Endovascular Surgery Unit, University of Siena, Viale Bracci, I-53100 Siena, Italy.
Eur J Vasc Endovasc Surg. 2007 Dec;34(6):655-62. doi: 10.1016/j.ejvs.2007.07.008. Epub 2007 Sep 20.
This study aims to determine safety, short and mid-term outcomes of Carotid Artery Stenting (CAS) and Endarterectomy (CEA) during the last 6 years in a single vascular surgery center.
We retrospectively reviewed 2624 consecutive carotid revascularizations performed between December 2000 and December 2006 in 2176 patients with severe carotid artery stenosis (symptomatic > or = 70%, asymptomatic > or = 80%), of which 1589 were CEA and 1035 CAS. Patients were followed up at 1, 3, 6 and 12 months after the procedure and then yearly.
The percutaneous procedure was successful in 99.2% of the cases. No intra-procedural death occurred. The overall death and stroke rates at 30 days, 1 year and 3 years were 1.54%, 2.86%, 7.43% in the CAS group and 2.07%, 3.55%, 6.95% in the CEA group, respectively (p value not significant in any case).
At our vascular surgery centre the results of CEA and CAS are similar. CAS has become our standard of care in preventing strokes and is an effective alternative to CEA for low-risk patients as well.
本研究旨在确定在单一血管外科中心过去6年中颈动脉支架置入术（CAS）和颈动脉内膜切除术（CEA）的安全性、短期和中期结果。
我们回顾性分析了2000年12月至2006年12月期间在2176例严重颈动脉狭窄患者（有症状的≥70%，无症状的≥80%）中进行的2624例连续颈动脉血运重建术，其中1589例为CEA，1035例为CAS。术后1、3、6和12个月对患者进行随访，之后每年随访一次。
经皮手术成功率为99.2%。术中无死亡发生。CAS组30天、1年和3年的总死亡率和卒中率分别为1.54%、2.86%、7.43%，CEA组分别为2.07%、3.55%、6.95%（在任何情况下p值均无统计学意义）。
在我们的血管外科中心，CEA和CAS的结果相似。CAS已成为我们预防卒中的标准治疗方法，也是低风险患者CEA的有效替代方法。
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