Witkowska J, Czerwińska D, Kiepurski A, Roszkowski W
Zakładu Podstaw Zywienia Instytutu Zywienia Człowieka SGGW-AR w Warszawie.
Rocz Panstw Zakl Hig. 1991;42(1):15-23.
A literature survey was made of the interactions--in the organism--between some food contaminating elements (mercury, tin, nickel, selenium, fluorine, aluminium) and iron, zinc and copper. The harmful elements may disturb the mineral metabolism already at the stage of intestinal absorption. Moreover, they bring about changes in microelement distribution in the tissues and cells. On account of their approximately similar chemical structure, they compete for the sites of binding to some proteins, including enzymic ones. In this respect a special role is played by ++metallothionein, a protein with the ability of regulating free metal contents in the tissues and thus possibly displaying some detoxifying properties. Many mechanisms and relationships determining the interactions between the surveyed food contaminants and iron, zinc and copper remain, however, not elucidated.
对某些食物污染元素（汞、锡、镍、硒、氟、铝）与铁、锌和铜在生物体内的相互作用进行了文献综述。有害元素在肠道吸收阶段就可能干扰矿物质代谢。此外，它们会引起组织和细胞中微量元素分布的变化。由于它们的化学结构大致相似，它们会竞争与某些蛋白质（包括酶蛋白）的结合位点。在这方面，金属硫蛋白发挥着特殊作用，它是一种能够调节组织中游离金属含量从而可能具有某些解毒特性的蛋白质。然而，许多决定所研究的食物污染物与铁、锌和铜之间相互作用的机制和关系仍未阐明。
