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地中海条纹原海豚(Stenella coeruleoalba meyen)组织和器官中汞、锌和硒的生物累积。它们相互作用的毒理学结果。

Mercury, zinc and selenium bioaccumulation in tissues and organs of Mediterranean striped dolphins Stenella coeruleoalba meyen. Toxicological result of their interaction.

作者信息

Augier H, Benkoël L, Chamlian A, Park W K, Ronneau C

机构信息

Centre d'Etudes, de Recherches et d'Informations sur la Mer (CERIMER), Faculté des Sciences de Luminy, Marseille, France.

出版信息

Cell Mol Biol (Noisy-le-grand). 1993 Sep;39(6):621-34.

PMID:8220072
Abstract

Neutron activation analysis of 13 Mediterranean striped dolphins Stenella coeruleoalba showed high mercury and selenium contaminations of main tissues and organs of these cetaceans. The mercuric contents were excessive, particularly in liver (from 68 to 2272 micrograms/g dry wt. basis), then in kidney, lung, muscle, heart and brain. The selenium concentrations were also high in liver (from 45 to 1320 micrograms/g dry wt. basis), then in kidney, lung, muscle, skin and heart. The main way of contamination seems to be the food through trophic network, but skin and lung are also able to play a part which must be elucidated. The average Hg/Se ratios in liver and kidney were respectively 1.82 and 1.59. Linear relationship between mercury and selenium concentrations in tissues and organs, particularly in liver and kidney, were confirmed. The mercury and selenium interaction on a toxicological point of view was established by a statistical approach; in the same way, intervention of zinc, metallothioneins and glutathiones have been discussed.

摘要

对13只地中海条纹原海豚(Stenella coeruleoalba)进行的中子活化分析表明,这些鲸类动物的主要组织和器官存在高汞和高硒污染。汞含量超标,尤其是在肝脏中(以干重计,从68至2272微克/克),其次是肾脏、肺、肌肉、心脏和大脑。肝脏中的硒浓度也很高(以干重计,从45至1320微克/克),其次是肾脏、肺、肌肉、皮肤和心脏。污染的主要途径似乎是通过营养网络的食物,但皮肤和肺也可能起到一定作用,这一点必须加以阐明。肝脏和肾脏中的平均汞/硒比率分别为1.82和1.59。组织和器官中汞和硒浓度之间的线性关系得到证实,尤其是在肝脏和肾脏中。从毒理学角度通过统计方法确定了汞和硒的相互作用;同样,也讨论了锌、金属硫蛋白和谷胱甘肽的作用。

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