Jørgensen J C, Ottesen B
Department of Obstetrics and Gynecology, University of Copenhagen, Denmark.
Acta Physiol Scand Suppl. 1991;603:59-65.
The 133Xe washout method has been evaluated and found to be a reliable method for the measurement of myometrial as well as ovarian blood flow rates in the rabbit. Monoexponential washout curves for 133Xe have been demonstrated for the whole washout process, both in the uterus and the ovary. Consequently it is possible to calculate the blood flow rate at any time interval during the whole washout process. This 133Xe washout technique has been used for the evaluation of the biological effect of neuropeptides on the local blood flow within the rabbit uterus and ovary. It has been recognized for years that the intrinsic control of a number of functions, including the blood flow regulation, in the genital tract cannot be attributed to cholinergic and/or adrenergic nerves alone. Evidence from 133Xe experiments suggests that the neuropeptides in the female genital tract may play a functional role in these non cholinergic non adrenergic events.
133Xe清除法已得到评估，结果表明它是测量兔子子宫肌层以及卵巢血流速率的可靠方法。对于整个清除过程，无论是在子宫还是卵巢，均已证明133Xe的单指数清除曲线。因此，在整个清除过程中的任何时间间隔都可以计算出血流速率。这种133Xe清除技术已用于评估神经肽对兔子子宫和卵巢内局部血流的生物学效应。多年来人们已经认识到，包括血流调节在内的许多生殖系统功能的内在控制不能仅归因于胆碱能和/或肾上腺素能神经。来自133Xe实验的证据表明，女性生殖系统中的神经肽可能在这些非胆碱能非肾上腺素能事件中发挥功能作用。
