黄斑、猴子、模型、年龄相关性黄斑变性与衰老
Maculas, monkeys, models, AMD and aging.
作者信息
Dawson William W, Dawson Judyth C, Lake Kenneth P, Gonzalez-Martinez Janis
机构信息
Department of Ophthalmology, University of Florida, 1600 SW Archer Road, Rm: M119, Gainesville, FL 32610-0284, USA.
出版信息
Vision Res. 2008 Feb;48(3):360-5. doi: 10.1016/j.visres.2007.08.006. Epub 2007 Sep 24.
PMID:17892891
Abstract
Age related macular degeneration (AMD) signs may be found reliably in monkeys (Macaca mulatta) bred selectively in Florida after 14 generations of inbreeding in a closed colony at the University of Puerto Rico. Progression, ultrastructure and functional losses are parallel to those found in humans.
摘要
在波多黎各大学一个封闭群落中经过14代近亲繁殖后在佛罗里达州选择性培育的猕猴（恒河猴）中，可以可靠地发现与年龄相关的黄斑变性（AMD）体征。其进展、超微结构和功能丧失与人类中发现的情况相似。
Zotero 插件