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无缝线板层角膜移植术:一种应用纤维蛋白胶的改良方法。

Sutureless lamellar keratoplasty: a modified approach for fibrin glue application.

作者信息

Duarte Maria Cecília Barros, Kim Terry

机构信息

Duke University Medical Center, Duke University Eye Center, Durham, NC 27710, USA.

出版信息

Cornea. 2007 Oct;26(9):1127-8. doi: 10.1097/ICO.0b013e31812e620c.

Abstract

PURPOSE

To report a case where fibrin glue was applied with a modified approach to secure the graft to the host bed in lamellar keratoplasty.

METHODS

One patient with epithelial membrane dystrophy, Salzmann nodular degeneration, and amyloid deposits in the cornea underwent lamellar keratoplasty by using fibrin glue. The glue components were applied separately: the fibrin component on the stromal bed and thrombin component on the stromal side of the lamellar graft. Tissue adhesion, corneal condition, and visual acuity were evaluated postoperatively.

RESULTS

Best-corrected visual acuity 4 months after surgery was 20/30. The graft remained clear and well positioned 9 months after surgery.

CONCLUSIONS

We report a case of visual acuity improvement and efficient adhesion of the lamellar graft after lamellar keratoplasty by using fibrin adhesive. The components of the glue can be applied separately, allowing more time to position the graft on the stromal bed.

摘要

目的

报告一例在板层角膜移植术中采用改良方法应用纤维蛋白胶将移植物固定于植床的病例。

方法

一名患有上皮膜营养不良、萨尔茨曼结节状变性和角膜淀粉样沉积的患者接受了使用纤维蛋白胶的板层角膜移植术。胶的成分分别应用:纤维蛋白成分涂于基质床,凝血酶成分涂于板层移植物的基质侧。术后评估组织粘连情况、角膜状况和视力。

结果

术后4个月最佳矫正视力为20/30。术后9个月移植物保持清晰且位置良好。

结论

我们报告了一例使用纤维蛋白粘合剂进行板层角膜移植术后视力改善且板层移植物有效粘连的病例。胶的成分可分别应用,从而有更多时间将移植物放置在基质床上。

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