Cambou J-P, Simon T, Mulak G, Bataille V, Danchin N
Société française de cardiologie, 5 rue des Colonnes du Trône, 75012 Paris.
Arch Mal Coeur Vaiss. 2007 Jun-Jul;100(6-7):524-34.
The FAST MI registry was designed to evaluate the 'real world' management of patients with acute myocardial infarction (MI), and to assess their in-hospital, medium- and long-term outcomes. Patients were recruited consecutively from intensive care units over a period of one month (from October 2005), with an additional one-month recruitment period for diabetic patients. The study included 3059 MI patients in phase 1 and an additional 611 diabetic patients in phase 2. Altogether, 53% of the patients had a final diagnosis of Q wave MI and 47% had non Q wave MI. Patients with Q wave MI were more likely to be men, younger, more frequently with a family history or a history of smoking. Patients with non Q wave MI had worst baseline demographic and clinical characteristics mainly explained by their older age. Time from symptom onset to hospital admission was less than three hours for 22% of the patients with Q wave MI and for 14% of the non Q wave MI patients. Among patients with Q wave MI, 64% received reperfusion therapy, 35% with primary percutaneous coronary interventions, 19% with pre-hospital thrombolysis and 10% with in-hospital thrombolysis. Over 70% of patients received statin therapy during the hospital stay and over 90% anti platelet agents. In-hospital mortality was 5.8% in patients with Q wave MI and 4.9% in patients with non Q Wave MI. At discharge beta-adrenergic blockers and statins and, to a lesser extent, medications of the renin angiotensin system were commonly prescribed. Over 90% received antiplatelet agents.
快速心肌梗死（MI）注册研究旨在评估急性心肌梗死患者的“真实世界”管理情况，并评估他们的住院、中长期结局。在一个月的时间里（从2005年10月开始），从重症监护病房连续招募患者，糖尿病患者另有一个月的招募期。该研究第一阶段纳入了3059例MI患者，第二阶段又纳入了611例糖尿病患者。总体而言，53%的患者最终诊断为Q波MI，47%为非Q波MI。Q波MI患者更可能为男性、更年轻，更频繁地有家族史或吸烟史。非Q波MI患者的基线人口统计学和临床特征最差，主要原因是他们年龄较大。Q波MI患者中22%、非Q波MI患者中14%从症状发作到入院的时间少于3小时。在Q波MI患者中，64%接受了再灌注治疗，35%接受了直接经皮冠状动脉介入治疗，19%接受了院前溶栓治疗，10%接受了院内溶栓治疗。超过70%的患者在住院期间接受了他汀类药物治疗，超过90%接受了抗血小板药物治疗。Q波MI患者的住院死亡率为5.8%，非Q波MI患者为4.9%。出院时，β受体阻滞剂和他汀类药物以及在较小程度上肾素血管紧张素系统药物通常被处方。超过90%的患者接受了抗血小板药物治疗。
