Departemt of Cardiology, Chonnam National University Hospital, Gwangju, Korea.
Department of Cardiology, Chungbuk National University Hospital, Cheongju, Korea.
Korean J Intern Med. 2019 Jan;34(1):1-10. doi: 10.3904/kjim.2018.381. Epub 2018 Dec 28.
Coronary artery disease, especially acute myocardial infarction (AMI), is a leading cause of death in the Asia-Pacific region. The Korea Acute Myocardial Infarction Registry (KAMIR) is the first nationwide, prospective, multicenter registry of Korean patients with AMI. Since the KAMIR first began in November 2005, more than 70,000 patients have been enrolled, and 230 papers have been published (as of October 2018). Moreover, published data from the KAMIR have revealed different characteristics from those of Western AMI registries regarding risk factors, interventional strategies, and clinical outcomes. As a result, the KAMIR study has improved the outcomes of percutaneous coronary intervention and reduced mortality. We propose the use of the KAMIR score in the prediction of 1-year mortality. Using data from the KAMIR, we provide an overview of the current status of AMI in Korea, including trends in demographic characteristics, risk factors, medications, treatment strategies, and clinical outcomes.
冠心病,尤其是急性心肌梗死(AMI),是亚太地区的主要死亡原因。韩国急性心肌梗死注册研究(KAMIR)是首个针对韩国 AMI 患者的全国性、前瞻性、多中心注册研究。自 2005 年 11 月首次开展以来,已经有超过 7 万名患者入组,发表了 230 篇论文(截至 2018 年 10 月)。此外,KAMIR 的发表数据显示,在危险因素、介入策略和临床结局方面,与西方 AMI 注册研究存在不同特征。因此,KAMIR 研究改善了经皮冠状动脉介入治疗的结局并降低了死亡率。我们建议使用 KAMIR 评分来预测 1 年死亡率。我们利用 KAMIR 数据,概述了韩国目前 AMI 的状况,包括人口统计学特征、危险因素、药物治疗、治疗策略和临床结局的趋势。