Drapeau Vicky, Lemieux Isabelle, Richard Denis, Bergeron Jean, Tremblay Angelo, Biron Simon, Marceau Picard, Mauriège Pascale
Division of Kinesiology, Department of Social and Preventive Medicine, Laval University, Québec, Canada.
Obes Surg. 2007 Jul;17(7):905-9. doi: 10.1007/s11695-007-9168-1.
The present retrospective study aims to provide additional evidence supporting the fact that waist circumference, in severe obesity, is not a good clinical marker to identify individuals with the metabolic syndrome or an altered metabolic profile.
Relationships between waist circumference and metabolic profile of pre- (n=165) and postmenopausal (n=43) severely obese women were compared to associations observed in pre- (n=52) and postmenopausal (n=35) moderately obese women.
Results showed that abdominal obesity assessed by waist circumference was more highly correlated with fasting glycemia, HDL-cholesterol and the cholesterol/HDL-cholesterol ratio in moderately than in severely obese women, before menopause. After menopause, waist circumference was not a valuable predictor of metabolic abnormalities in both groups. Moreover, when waist circumference was included as a criterion of the metabolic syndrome (as defined by the NCEP ATP III guidelines) in severely obese women, the prevalence of this metabolic condition was over-estimated by 72%.
These results emphasize the uselessness of waist circumference to assess the prevalence of the metabolic syndrome or an altered metabolic profile in severely obese women.
本回顾性研究旨在提供更多证据，支持以下事实：在重度肥胖患者中，腰围并非识别代谢综合征或代谢状况改变个体的良好临床指标。
将重度肥胖的绝经前（n = 165）和绝经后（n = 43）女性的腰围与代谢状况之间的关系，与中度肥胖的绝经前（n = 52）和绝经后（n = 35）女性中观察到的关联进行比较。
结果显示，在绝经前，通过腰围评估的腹部肥胖与中度肥胖女性的空腹血糖、高密度脂蛋白胆固醇及胆固醇/高密度脂蛋白胆固醇比值的相关性，高于重度肥胖女性。绝经后，腰围在两组中均不是代谢异常的有效预测指标。此外，当将腰围作为重度肥胖女性代谢综合征（根据美国国家胆固醇教育计划成人治疗组第三次报告指南定义）的一项标准时，该代谢状况的患病率被高估了72%。
这些结果强调了腰围在评估重度肥胖女性代谢综合征患病率或代谢状况改变方面毫无用处。
